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NCT00352365 · ClinicalTrials.gov registry record · Phase 2

Lenalidomide in Treating Older Patients With Acute Myeloid Leukemia

A Phase 2 study of Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities and Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 2
Development phase
41
Enrollment target
20
Study locations

NCT00352365 is a Phase 2 study of Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities and Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 41 participants, below the 117-participant average among 29 other Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities trials with a reported enrollment target (65% lower). The trial reports 20 study locations across 7 states.

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The verdict

NCT00352365, a Phase 2 study of Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities and Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 2
Development phase
41 participants
Enrollment target
20
Study locations

Study Summary

This phase II trial is studying how well lenalidomide works in treating older patients with acute myeloid leukemia with abnormal chromosome 5q. Biological therapies, such as lenalidomide, may stimulate the immune system in different ways and stop cancer cells from growing.

Interventions

  • DRUG lenalidomide

Study Locations (20)

Montana

  • Montana Cancer Consortium CCOP - Billings
  • Northern Rockies Radiation Oncology Center - Billings
  • Saint Vincent Healthcare - Billings
  • Hematology-Oncology Centers of the Northern Rockies PC - Billings
  • Billings Clinic - Billings
  • Deaconess Medical Center - Billings
  • Bozeman Deaconess Cancer Center - Bozeman
  • Bozeman Deaconess Hospital - Bozeman
  • Saint James Community Hospital and Cancer Treatment Center - Butte
  • Berdeaux, Donald MD (UIA Investigator) - Great Falls

California

  • Shasta Regional Medical Center - Redding
  • Sutter Roseville Medical Center - Roseville
  • Sutter General Hospital - Sacramento

Illinois

  • Cancer Care Center of Decatur - Decatur
  • Decatur Memorial Hospital - Decatur
  • Memorial Medical Center - Springfield

Arkansas

  • University of Arkansas for Medical Sciences - Little Rock

Florida

  • H. Lee Moffitt Cancer Center and Research Institute - Tampa

Kansas

  • Salina Regional Health Center - Salina

Michigan

  • University of Michigan - Ann Arbor

Trial Details

FieldValue
Enrollment Target 41 participants
Start Date 2006-06
Est. Completion 2011-07-01
Phase Phase 2

Sponsor

National Cancer Institute (NCI)

3,257 total trials

What the Registry Record Tells You About NCT00352365

The ClinicalTrials.gov registry entry for NCT00352365 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 41 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 117-participant average among 29 other Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities trials with a reported enrollment target (65% lower). The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.

The record links to 10 conditions, with Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities appearing as the primary indexed condition, and to 1 intervention - of which lenalidomide is the first listed.

NCT00352365 reports 20 study locations spanning 7 distinct geographic areas - top geographies include Montana, California, Illinois.

Frequently Asked Questions

What is clinical trial NCT00352365 about?

NCT00352365 is a clinical study titled "Lenalidomide in Treating Older Patients With Acute Myeloid Leukemia". This phase II trial is studying how well lenalidomide works in treating older patients with acute myeloid leukemia with abnormal chromosome 5q. Biological therapies, such as lenalidomide, may stimulate the immune system in different ways and stop cancer cells from growing.

What is the current status of trial NCT00352365?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 41 participants. The study started on 2006-06. Estimated completion is 2011-07-01.

What conditions does trial NCT00352365 study?

This clinical trial studies the following conditions: Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Minimally Differentiated Myeloid Leukemia (M0), Adult Acute Monocytic Leukemia (M5b), Adult Acute Myeloblastic Leukemia With Maturation (M2).

What interventions are being tested in trial NCT00352365?

The interventions under investigation include: lenalidomide (DRUG).

Who is sponsoring clinical trial NCT00352365?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00352365 being conducted?

This trial has 20 study locations across Arkansas, California, Florida, Illinois, Kansas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.