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NCT00352118 · ClinicalTrials.gov registry record · Phase 2

Combination Chemotherapy and Radiation Therapy in Treating Patients With Locally Advanced Head and Neck Cancer

A Phase 2 study, sponsored by Masonic Cancer Center, University of Minnesota.

Terminated
Registry status
Phase 2
Development phase
4
Enrollment target

NCT00352118: Clinical Trial Phase 2 study, sponsored by Masonic Cancer Center, University of Minnesota.

NCT00352118 is a Phase 2 study that was terminated before completion, run by Masonic Cancer Center, University of Minnesota. The registered enrollment target is 4 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00352118, a Phase 2 study, was terminated before completion, sponsored by Masonic Cancer Center, University of Minnesota.

TERMINATED
Registry status
Phase 2
Development phase
4 participants
Enrollment target

Study Summary

RATIONALE: Drugs used in chemotherapy, such as docetaxel, cisplatin, and fluorouracil, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Radiation therapy uses high-energy x-rays to kill tumor cells. Giving combination chemotherapy together with radiation therapy may kill more tumor cells. PURPOSE: This phase II trial is studying how well giving combination chemotherapy together with radiation therapy works in treating patients with locally advanced head and neck cancer. The doctor also wants to find out if patients who receive this treatment need a feeding tube 1 year after starting treatment.

Primary Outcome

All patients were non-evaluable and study was terminated early. There is no measure of outcome.

Interventions

  • DRUG cisplatin
  • DRUG docetaxel
  • DRUG fluorouracil
  • BIOLOGICAL filgrastim
  • BIOLOGICAL pegfilgrastim

Trial Details

FieldValue
Enrollment Target 4 participants
Start Date 2006-03
Est. Completion 2008-04
Phase Phase 2

Why NCT00352118 stopped before completion

NCT00352118 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (97% lower).

The record links to 0 conditions, and to 5 interventions - of which cisplatin is the first listed.

NCT00352118 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00352118 about?

NCT00352118 is a clinical study titled "Combination Chemotherapy and Radiation Therapy in Treating Patients With Locally Advanced Head and Neck Cancer". RATIONALE: Drugs used in chemotherapy, such as docetaxel, cisplatin, and fluorouracil, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Radiation therapy uses high-energy x-rays to kill tumor cells. Giving combination chemothera...

What is the current status of trial NCT00352118?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 4 participants. The study started on 2006-03. Estimated completion is 2008-04.

What interventions are being tested in trial NCT00352118?

The interventions under investigation include: cisplatin (DRUG), docetaxel (DRUG), fluorouracil (DRUG), filgrastim (BIOLOGICAL), pegfilgrastim (BIOLOGICAL).

Who is sponsoring clinical trial NCT00352118?

This trial is sponsored by Masonic Cancer Center, University of Minnesota, which has 249 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00352118's enrollment target sits among peer trials

4 2001st of 2000 the lowest of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00352118, the US trial registry maintained by the National Library of Medicine. NCT00352118 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.