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NCT00350844 · ClinicalTrials.gov registry record · Phase 1
Hydroxyurea for Children and Young Adults With Sickle Cell Disease and Pulmonary Hypertension
A Phase 1 study, sponsored by Ann & Robert H Lurie Children's Hospital of Chicago.
- Terminated
- Registry status
- Phase 1
- Development phase
- 6
- Enrollment target
NCT00350844: Clinical Trial Phase 1 study, sponsored by Ann & Robert H Lurie Children's Hospital of Chicago.
NCT00350844 is a Phase 1 study that was terminated before completion, run by Ann & Robert H Lurie Children's Hospital of Chicago. The registered enrollment target is 6 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (90% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00350844, a Phase 1 study, was terminated before completion, sponsored by Ann & Robert H Lurie Children's Hospital of Chicago.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 6 participants
- Enrollment target
Study Summary
The goal of this study is to test the hypothesis that hydroxyurea is effective for the specific treatment of secondary pulmonary hypertension found on screening in children and young adults with sickle cell disease.
Primary Outcome
Primary outcome measure was tricuspid regurgitant jet velocity (TRJV) by echocardiogram after 6 and 12 months of hydroxyurea therapy.
Interventions
- DRUG Hydroxyurea
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 6 participants |
| Start Date | 2006-07 |
| Est. Completion | 2008-06 |
| Phase | Phase 1 |
Why NCT00350844 stopped before completion
NCT00350844 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 6 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (90% lower).
The record links to 0 conditions, and to 1 intervention - of which Hydroxyurea is the first listed.
NCT00350844 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00350844 about?
NCT00350844 is a clinical study titled "Hydroxyurea for Children and Young Adults With Sickle Cell Disease and Pulmonary Hypertension". The goal of this study is to test the hypothesis that hydroxyurea is effective for the specific treatment of secondary pulmonary hypertension found on screening in children and young adults with sickle cell disease.
What is the current status of trial NCT00350844?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 6 participants. The study started on 2006-07. Estimated completion is 2008-06.
What interventions are being tested in trial NCT00350844?
The interventions under investigation include: Hydroxyurea (DRUG).
Who is sponsoring clinical trial NCT00350844?
This trial is sponsored by Ann & Robert H Lurie Children's Hospital of Chicago, which has 159 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00350844's enrollment target sits among peer trials
6 1974th of 2000 higher than 12 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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