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NCT00343148 · ClinicalTrials.gov registry record · Phase 1
Pharmacokinetic Study of a Single Dose of AVI-4126 (RESTEN-NG®) in Cerebral Spinal Fluid
A Phase 1 study, sponsored by Sarepta Therapeutics.
- Completed
- Registry status
- Phase 1
- Development phase
- 6
- Enrollment target
NCT00343148: Completed Phase 1 study, sponsored by Sarepta Therapeutics.
NCT00343148 is a Phase 1 study that has completed, run by Sarepta Therapeutics. The registered enrollment target is 6 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (90% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00343148, a Phase 1 study, has completed, sponsored by Sarepta Therapeutics.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 6 participants
- Enrollment target
Study Summary
Because AVI-4020 Injection was found to cross the blood-brain barrier, and because AVI-4126 (RESTEN-NG) has potential medical benefit to people with a variety of diseases, including cancers, this study is being performed to find out if AVI-4126 also crosses the blood-brain barrier. If it does, then additional investigations could be performed, such as in people with certain types of cancer.
Interventions
- DRUG AVI-4126 Injection (RESTEN-NG®)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 6 participants |
| Start Date | 2006-06 |
| Est. Completion | 2009-06 |
| Phase | Phase 1 |
What the finished NCT00343148 record still lists
NCT00343148 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 6 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (90% lower).
The record links to 0 conditions, and to 1 intervention - of which AVI-4126 Injection (RESTEN-NG®) is the first listed.
NCT00343148 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00343148 about?
NCT00343148 is a clinical study titled "Pharmacokinetic Study of a Single Dose of AVI-4126 (RESTEN-NG®) in Cerebral Spinal Fluid". Because AVI-4020 Injection was found to cross the blood-brain barrier, and because AVI-4126 (RESTEN-NG) has potential medical benefit to people with a variety of diseases, including cancers, this study is being performed to find out if AVI-4126 also crosses the blood-brain barrier. If it does, then ...
What is the current status of trial NCT00343148?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 6 participants. The study started on 2006-06. Estimated completion is 2009-06.
What interventions are being tested in trial NCT00343148?
The interventions under investigation include: AVI-4126 Injection (RESTEN-NG®) (DRUG).
Who is sponsoring clinical trial NCT00343148?
This trial is sponsored by Sarepta Therapeutics, which has 33 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00343148's enrollment target sits among peer trials
6 1974th of 2000 higher than 12 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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