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NCT00336479 · ClinicalTrials.gov registry record · Phase 2

Phase 2 Study of VX-950, Pegasys®, and Copegus® in Hepatitis C

A Phase 2 study, sponsored by Vertex Pharmaceuticals Incorporated.

Completed
Registry status
Phase 2
Development phase
263
Enrollment target

NCT00336479: Completed Phase 2 study, sponsored by Vertex Pharmaceuticals Incorporated.

NCT00336479 is a Phase 2 study that has completed, run by Vertex Pharmaceuticals Incorporated. The registered enrollment target is 263 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (98% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00336479, a Phase 2 study, has completed, sponsored by Vertex Pharmaceuticals Incorporated.

COMPLETED
Registry status
Phase 2
Development phase
263 participants
Enrollment target

Study Summary

Study the effectiveness of telaprevir (VX-950) in combination with Pegylated Interferon Alfa 2a (Peg-IFN-alfa-2a) and Ribavirin (RBV) in reducing plasma hepatitis C virus (HCV) ribonucleic acid (RNA) levels

Primary Outcome

The plasma HCV RNA level was measured using Roche TaqMan HCV RNA assay. The lower limit of detection was 10 international units per milliliter (IU/mL).

Interventions

  • OTHER Placebo
  • DRUG Ribavirin
  • DRUG Telaprevir
  • DRUG Pegylated Interferon Alfa 2a

Trial Details

FieldValue
Enrollment Target 263 participants
Start Date 2006-06
Est. Completion 2008-02
Phase Phase 2
Vertex Pharmaceuticals Incorporated

191 total trials

What the finished NCT00336479 record still lists

NCT00336479 is an interventional study that assigns participants to a tested intervention. The registered 263 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (98% higher).

The record links to 0 conditions, and to 4 interventions - of which Placebo is the first listed.

NCT00336479 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00336479 about?

NCT00336479 is a clinical study titled "Phase 2 Study of VX-950, Pegasys®, and Copegus® in Hepatitis C". Study the effectiveness of telaprevir (VX-950) in combination with Pegylated Interferon Alfa 2a (Peg-IFN-alfa-2a) and Ribavirin (RBV) in reducing plasma hepatitis C virus (HCV) ribonucleic acid (RNA) levels

What is the current status of trial NCT00336479?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 263 participants. The study started on 2006-06. Estimated completion is 2008-02.

What interventions are being tested in trial NCT00336479?

The interventions under investigation include: Placebo (OTHER), Ribavirin (DRUG), Telaprevir (DRUG), Pegylated Interferon Alfa 2a (DRUG).

Who is sponsoring clinical trial NCT00336479?

This trial is sponsored by Vertex Pharmaceuticals Incorporated, which has 191 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00336479's enrollment target sits among peer trials

263 210th of 2000 higher than 1,791 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00336479, the US trial registry maintained by the National Library of Medicine. NCT00336479 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.