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NCT00334815 · ClinicalTrials.gov registry record · Phase 2
Combination Chemotherapy, Radiation Therapy, and Bevacizumab in Treating Patients With Newly Diagnosed Stage III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery
A Phase 2 study of Lung Adenocarcinoma and Stage IIIA Lung Non-Small Cell Cancer AJCC v7, sponsored by National Cancer Institute (NCI).
- Active
- Registry status
- Phase 2
- Development phase
- 29
- Enrollment target
- 20
- Study locations
NCT00334815: Active Phase 2 study of Lung Adenocarcinoma and Stage IIIA Lung Non-Small Cell Cancer AJCC v7, sponsored by National Cancer Institute (NCI).
NCT00334815 is a Phase 2 study of Lung Adenocarcinoma and Stage IIIA Lung Non-Small Cell Cancer AJCC v7 that is active but no longer recruiting, run by National Cancer Institute (NCI). The registered enrollment target is 29 participants, below the 557-participant average among 14 other Lung Adenocarcinoma trials with a reported enrollment target (95% lower). The trial reports 20 study locations across 6 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00334815, a Phase 2 study of Lung Adenocarcinoma and Stage IIIA Lung Non-Small Cell Cancer AJCC v7, is active but no longer recruiting, sponsored by National Cancer Institute (NCI).
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 29 participants
- Enrollment target
- 20
- Study locations
Study Summary
This clinical trial studies combination chemotherapy, radiation therapy, and bevacizumab in treating patients with newly diagnosed stage III non-small cell lung cancer that cannot be removed by surgery. Drugs used in chemotherapy, such as cisplatin, etoposide, and docetaxel, work in different ways to stop the growth of \[cancer/tumor\] cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Radiation therapy uses high-energy x-rays to kill tumor cells. Monoclonal antibodies, such as bevacizumab, may interfere with the ability of tumor cells to grow and spread. Bevacizumab may also stop the growth of tumor cells by blocking blood flow to the tumor. Giving more than one drug (combination chemotherapy) together with radiation therapy and bevacizumab may kill more tumor cells.
Primary Outcome
Only adverse events that are possibly, probably or definitely related to study drug are reported.
Conditions Studied
Interventions
- DRUG Docetaxel
- DRUG Cisplatin
- DRUG Etoposide
- BIOLOGICAL Filgrastim
- BIOLOGICAL Bevacizumab
Study Locations (20)
California
- USC / Norris Comprehensive Cancer Center - Los Angeles
- Fremont - Rideout Cancer Center - Marysville
- UC Irvine Health/Chao Family Comprehensive Cancer Center - Orange
- University of California Davis Comprehensive Cancer Center - Sacramento
- Providence Santa Rosa Memorial Hospital - Santa Rosa
- Gene Upshaw Memorial Tahoe Forest Cancer Center - Truckee
- Northbay Cancer Center - Vacaville
Colorado
- Rocky Mountain Regional VA Medical Center - Aurora
- UCHealth University of Colorado Hospital - Aurora
- Denver Health Medical Center - Denver
- University of Colorado - Denver
- Shaw Cancer Center - Edwards
- Valley View Hospital Cancer Center - Glenwood Springs
- Montrose Memorial Hospital - Montrose
Arkansas
- Saint Bernards Regional Medical Center - Jonesboro
- University of Arkansas for Medical Sciences - Little Rock
- Highlands Oncology Group - Rogers - Rogers
Alabama
- Providence Hospital - Mobile
Florida
- Cancer Centers of Central Florida PA - Leesburg
Georgia
- Lewis Cancer and Research Pavilion at Saint Joseph's/Candler - Savannah
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 29 participants |
| Start Date | 2006-06-15 |
| Est. Completion | 2026-02-22 |
| Phase | Phase 2 |
What the registry record for NCT00334815 still lists
NCT00334815 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 29 participants, a relatively small participant target, below the 557-participant average among 14 other Lung Adenocarcinoma trials with a reported enrollment target (95% lower).
The record links to 7 conditions, with Lung Adenocarcinoma appearing as the primary indexed condition, and to 5 interventions - of which Docetaxel is the first listed.
NCT00334815 names 20 study sites across 6 states, led by California, Colorado, Arkansas.
Frequently Asked Questions
What is clinical trial NCT00334815 about?
NCT00334815 is a clinical study titled "Combination Chemotherapy, Radiation Therapy, and Bevacizumab in Treating Patients With Newly Diagnosed Stage III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery". This clinical trial studies combination chemotherapy, radiation therapy, and bevacizumab in treating patients with newly diagnosed stage III non-small cell lung cancer that cannot be removed by surgery. Drugs used in chemotherapy, such as cisplatin, etoposide, and docetaxel, work in different ways t...
What is the current status of trial NCT00334815?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 29 participants. The study started on 2006-06-15. Estimated completion is 2026-02-22.
What conditions does trial NCT00334815 study?
This clinical trial studies the following conditions: Lung Adenocarcinoma, Stage IIIA Lung Non-Small Cell Cancer AJCC v7, Stage IIIB Lung Non-Small Cell Cancer AJCC v7, Lung Large Cell Carcinoma, Lung Squamous Cell Carcinoma.
What interventions are being tested in trial NCT00334815?
The interventions under investigation include: Docetaxel (DRUG), Cisplatin (DRUG), Etoposide (DRUG), Filgrastim (BIOLOGICAL), Bevacizumab (BIOLOGICAL).
Who is sponsoring clinical trial NCT00334815?
This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00334815 being conducted?
This trial has 20 study locations across Alabama, Arkansas, California, Colorado, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Lung Adenocarcinoma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00334815's enrollment target sits among peer trials
29 14th of 14 higher than 1 of 14 other Lung Adenocarcinoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Lung Adenocarcinoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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