Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00332644 · ClinicalTrials.gov registry record · Phase 4

Smoking Cessation Medications: Efficacy, Mechanisms and Algorithms

A Phase 4 study, sponsored by University of Wisconsin, Madison.

Completed
Registry status
Phase 4
Development phase
1,504
Enrollment target

NCT00332644: Completed Phase 4 study, sponsored by University of Wisconsin, Madison.

NCT00332644 is a Phase 4 study that has completed, run by University of Wisconsin, Madison. The registered enrollment target is 1,504 participants, above the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (190% higher). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00332644, a Phase 4 study, has completed, sponsored by University of Wisconsin, Madison.

COMPLETED
Registry status
Phase 4
Development phase
1,504 participants
Enrollment target

Study Summary

The proposed work will advance the understanding and effectiveness of tobacco dependence treatment and result in more smokers quitting successfully.

Primary Outcome

Smoking status was assessed both as 7-day point-prevalence abstinence ("Have you smoked at all, even a puff, in the last 7 days?") and continuous abstinence (smoking at all since the target quit day), using a smoking calendar and the timeline follow-back method. All participants' self-reports of smoking status during study visits were confirmed by an expired carbon monoxide level of less than 10 ppm measured using a Micro-3 Smokerlyzer (Bedfont Scientific, Williamsburg, Virginia).

Interventions

  • DRUG nicotine patch
  • DRUG bupropion
  • DRUG nicotine lozenge
  • DRUG nicotine patch + nicotine lozenge
  • DRUG bupropion + lozenge

Trial Details

FieldValue
Enrollment Target 1,504 participants
Start Date 2004-09
Est. Completion 2010-08
Phase Phase 4
University of Wisconsin, Madison

1,039 total trials

What the finished NCT00332644 record still lists

NCT00332644 is an interventional study that assigns participants to a tested intervention. Its 1,504 participants enrollment target places it among the larger protocols in the corpus, above the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (190% higher).

The record links to 0 conditions, and to 5 interventions - of which nicotine patch is the first listed.

NCT00332644 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00332644 about?

NCT00332644 is a clinical study titled "Smoking Cessation Medications: Efficacy, Mechanisms and Algorithms". The proposed work will advance the understanding and effectiveness of tobacco dependence treatment and result in more smokers quitting successfully.

What is the current status of trial NCT00332644?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 1,504 participants. The study started on 2004-09. Estimated completion is 2010-08.

What interventions are being tested in trial NCT00332644?

The interventions under investigation include: nicotine patch (DRUG), bupropion (DRUG), nicotine lozenge (DRUG), nicotine patch + nicotine lozenge (DRUG), bupropion + lozenge (DRUG).

Who is sponsoring clinical trial NCT00332644?

This trial is sponsored by University of Wisconsin, Madison, which has 1,039 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00332644's enrollment target sits among peer trials

1,504 51st of 2000 higher than 1,950 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT00178724 · 1,500 participants

    Spinal Cord Injury Registry - North American Clinical Trials Network

  • NCT00951366 · 1,500 participants

    Preterm Lung Patient Registry

  • NCT01050504 · 1,500 participants

    Collecting and Studying Blood and Tissue Samples From Patients With Locally Recurrent or Metastatic Prostate or Bladder/Urothelial Cancer

  • NCT02071134 · 1,500 participants

    Registry of Deep Brain Stimulation With the VERCISE™ System: Vercise DBS Registry

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00332644, the US trial registry maintained by the National Library of Medicine. NCT00332644 (large enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.