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NCT00326664 · ClinicalTrials.gov registry record · Phase 1

AZD2171 in Treating Young Patients With Recurrent, Progressive, or Refractory Primary CNS Tumors

A Phase 1 study, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 1
Development phase
55
Enrollment target

NCT00326664: Completed Phase 1 study, sponsored by National Cancer Institute (NCI).

NCT00326664 is a Phase 1 study that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 55 participants, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00326664, a Phase 1 study, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 1
Development phase
55 participants
Enrollment target

Study Summary

This phase I trial is studying the side effects and best dose of AZD2171 in treating young patients with recurrent, progressive, or refractory primary CNS tumors. AZD2171 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor.

Primary Outcome

Estimated using the modified Continual Reassessment Method (CRM).

Interventions

  • DRUG Cediranib Maleate

Trial Details

FieldValue
Enrollment Target 55 participants
Start Date 2006-03
Est. Completion 2015-07
Phase Phase 1
National Cancer Institute (NCI)

3,257 total trials

What the finished NCT00326664 record still lists

NCT00326664 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 55 participants, a relatively small participant target, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target.

The record links to 0 conditions, and to 1 intervention - of which Cediranib Maleate is the first listed.

NCT00326664 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00326664 about?

NCT00326664 is a clinical study titled "AZD2171 in Treating Young Patients With Recurrent, Progressive, or Refractory Primary CNS Tumors". This phase I trial is studying the side effects and best dose of AZD2171 in treating young patients with recurrent, progressive, or refractory primary CNS tumors. AZD2171 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor...

What is the current status of trial NCT00326664?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 55 participants. The study started on 2006-03. Estimated completion is 2015-07.

What interventions are being tested in trial NCT00326664?

The interventions under investigation include: Cediranib Maleate (DRUG).

Who is sponsoring clinical trial NCT00326664?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00326664's enrollment target sits among peer trials

55 918th of 2000 higher than 1,070 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00326664, the US trial registry maintained by the National Library of Medicine. NCT00326664 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.