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NCT00324480 · ClinicalTrials.gov registry record · Phase 1

Vorinostat and Alvocidib in Treating Patients With Advanced Solid Tumors

A Phase 1 study, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 1
Development phase
60
Enrollment target

NCT00324480: Completed Phase 1 study, sponsored by National Cancer Institute (NCI).

NCT00324480 is a Phase 1 study that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 60 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00324480, a Phase 1 study, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 1
Development phase
60 participants
Enrollment target

Study Summary

This phase I trial is studying the side effects and best dose of vorinostat when given together with alvocidib in treating patients with advanced solid tumors. Drugs used in chemotherapy, such as vorinostat and alvocidib, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Vorinostat may also stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving vorinostat together with alvocidib may kill more tumor cells.

Interventions

  • DRUG vorinostat
  • OTHER pharmacological study
  • DRUG alvocidib

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2006-03
Phase Phase 1

Sponsor

National Cancer Institute (NCI)

3,257 total trials

What the Registry Record Tells You About NCT00324480

The ClinicalTrials.gov registry entry for NCT00324480 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which vorinostat is the first listed.

NCT00324480 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00324480 about?

NCT00324480 is a clinical study titled "Vorinostat and Alvocidib in Treating Patients With Advanced Solid Tumors". This phase I trial is studying the side effects and best dose of vorinostat when given together with alvocidib in treating patients with advanced solid tumors. Drugs used in chemotherapy, such as vorinostat and alvocidib, work in different ways to stop the growth of tumor cells, either by killing th...

What is the current status of trial NCT00324480?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 60 participants. The study started on 2006-03.

What interventions are being tested in trial NCT00324480?

The interventions under investigation include: vorinostat (DRUG), pharmacological study (OTHER), alvocidib (DRUG).

Who is sponsoring clinical trial NCT00324480?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.