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NCT00322296 · ClinicalTrials.gov registry record · Phase 2

Phase II Trial to Evaluate the Efficacy of Topical Bexarotene Gel in Patients With Parapsoriasis

A Phase 2 study, sponsored by Fox Chase Cancer Center.

Terminated
Registry status
Phase 2
Development phase
8
Enrollment target

NCT00322296: Clinical Trial Phase 2 study, sponsored by Fox Chase Cancer Center.

NCT00322296 is a Phase 2 study that was terminated before completion, run by Fox Chase Cancer Center. The registered enrollment target is 8 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00322296, a Phase 2 study, was terminated before completion, sponsored by Fox Chase Cancer Center.

TERMINATED
Registry status
Phase 2
Development phase
8 participants
Enrollment target

Study Summary

Parapsoriasis is a term that refers to a precursor stage of cutaneous T-cell lymphoma (CTCL)/mycosis fungoides(MF). Complete responses (clearing) of early presentations of CTCL/MF have been shown to be associated with long-term survival and cure. Induction of a complete response in parapsoriasis, therefore, would seem to be a desirable therapeutic endpoint. Bexarotene 1% gel has been approved for treatment of cutaneous T-cell lymphoma (mycosis fungoides). The goal of this study is to evaluate the tolerability, safety and efficacy of bexarotene 1% gel in patients with parapsoriasis.

Interventions

  • DRUG Bexarotene 1% gel

Trial Details

FieldValue
Enrollment Target 8 participants
Start Date 2001-04
Est. Completion 2004-08
Phase Phase 2
Fox Chase Cancer Center

183 total trials

Why NCT00322296 stopped before completion

NCT00322296 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (94% lower).

The record links to 0 conditions, and to 1 intervention - of which Bexarotene 1% gel is the first listed.

NCT00322296 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00322296 about?

NCT00322296 is a clinical study titled "Phase II Trial to Evaluate the Efficacy of Topical Bexarotene Gel in Patients With Parapsoriasis". Parapsoriasis is a term that refers to a precursor stage of cutaneous T-cell lymphoma (CTCL)/mycosis fungoides(MF). Complete responses (clearing) of early presentations of CTCL/MF have been shown to be associated with long-term survival and cure. Induction of a complete response in parapsoriasis, th...

What is the current status of trial NCT00322296?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 8 participants. The study started on 2001-04. Estimated completion is 2004-08.

What interventions are being tested in trial NCT00322296?

The interventions under investigation include: Bexarotene 1% gel (DRUG).

Who is sponsoring clinical trial NCT00322296?

This trial is sponsored by Fox Chase Cancer Center, which has 183 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00322296's enrollment target sits among peer trials

8 1990th of 2000 higher than 5 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00322296, the US trial registry maintained by the National Library of Medicine. NCT00322296 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.