Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00319566 · ClinicalTrials.gov registry record · Phase 3

Heart and Estrogen-Progestin Replacement Study (HERS)

A Phase 3 study, sponsored by University of California, San Francisco.

Completed
Registry status
Phase 3
Development phase
2,430
Enrollment target

NCT00319566: Completed Phase 3 study, sponsored by University of California, San Francisco.

NCT00319566 is a Phase 3 study that has completed, run by University of California, San Francisco. The registered enrollment target is 2,430 participants, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (215% higher). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00319566, a Phase 3 study, has completed, sponsored by University of California, San Francisco.

COMPLETED
Registry status
Phase 3
Development phase
2,430 participants
Enrollment target

Study Summary

The purpose of the study is to determine whether hormone replacement therapy in post menopausal women with coronary artery disease prevents future heart attacks or death from coronary heart disease.

Interventions

  • DRUG Premarin .625 mg daily plus medroxyprogesterone 2.5 mg daily

Trial Details

FieldValue
Enrollment Target 2,430 participants
Start Date 1992-07
Est. Completion 2001-07
Phase Phase 3

What the finished NCT00319566 record still lists

NCT00319566 is an interventional study that assigns participants to a tested intervention. Its 2,430 participants enrollment target places it among the larger protocols in the corpus, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (215% higher).

The record links to 0 conditions, and to 1 intervention - of which Premarin .625 mg daily plus medroxyprogesterone 2.5 mg daily is the first listed.

NCT00319566 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00319566 about?

NCT00319566 is a clinical study titled "Heart and Estrogen-Progestin Replacement Study (HERS)". The purpose of the study is to determine whether hormone replacement therapy in post menopausal women with coronary artery disease prevents future heart attacks or death from coronary heart disease.

What is the current status of trial NCT00319566?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 2,430 participants. The study started on 1992-07. Estimated completion is 2001-07.

What interventions are being tested in trial NCT00319566?

The interventions under investigation include: Premarin .625 mg daily plus medroxyprogesterone 2.5 mg daily (DRUG).

Who is sponsoring clinical trial NCT00319566?

This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00319566's enrollment target sits among peer trials

2,430 89th of 2000 higher than 1,912 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT06676904 · 2,433 participants · NA

    Neonatal Platelet Transfusion Threshold Trial

  • NCT05345951 · 2,425 participants · NA

    Project e-PBI+ - Parent Intervention to Reduce College Student Drinking and Cannabis Use

  • NCT06128304 · 2,436 participants · NA

    ACCESS: Accelerating Cervical Cancer Elimination Through the Integration of Screen-and-treat Services

  • NCT05873387 · 2,420 participants

    Development of an Algorithm to Detect Pulmonary Hypertension Using an Electronic Stethoscope

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00319566, the US trial registry maintained by the National Library of Medicine. NCT00319566 (large enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.