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NCT00305734 · ClinicalTrials.gov registry record · Phase 2

Bortezomib and Gemcitabine in Treating Patients With Recurrent or Metastatic Nasopharyngeal Cancer

A Phase 2 study of Recurrent Nasopharyngeal Cancer and Stage IV Nasopharyngeal Cancer, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 2
Development phase
50
Enrollment target
1
Study location

NCT00305734: Completed Phase 2 study of Recurrent Nasopharyngeal Cancer and Stage IV Nasopharyngeal Cancer, sponsored by National Cancer Institute (NCI).

NCT00305734 is a Phase 2 study of Recurrent Nasopharyngeal Cancer and Stage IV Nasopharyngeal Cancer that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 50 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (62% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00305734, a Phase 2 study of Recurrent Nasopharyngeal Cancer and Stage IV Nasopharyngeal Cancer, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 2
Development phase
50 participants
Enrollment target
1
Study location

Study Summary

This phase II trial is studying how well giving bortezomib together with gemcitabine works in treating patients with recurrent or metastatic nasopharyngeal cancer. Bortezomib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as gemcitabine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving bortezomib together with gemcitabine may kill more tumor cells

Interventions

  • OTHER laboratory biomarker analysis
  • DRUG bortezomib
  • DRUG gemcitabine hydrochloride

Study Locations (1)

Texas

  • Southwest Oncology Group - San Antonio

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2006-08
Phase Phase 2
National Cancer Institute (NCI)

3,257 total trials

What the finished NCT00305734 record still lists

NCT00305734 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (62% lower).

The record links to 2 conditions, with Recurrent Nasopharyngeal Cancer appearing as the primary indexed condition, and to 3 interventions - of which laboratory biomarker analysis is the first listed.

NCT00305734 reports a single indexed study location in Texas.

Frequently Asked Questions

What is clinical trial NCT00305734 about?

NCT00305734 is a clinical study titled "Bortezomib and Gemcitabine in Treating Patients With Recurrent or Metastatic Nasopharyngeal Cancer". This phase II trial is studying how well giving bortezomib together with gemcitabine works in treating patients with recurrent or metastatic nasopharyngeal cancer. Bortezomib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such a...

What is the current status of trial NCT00305734?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 50 participants. The study started on 2006-08.

What conditions does trial NCT00305734 study?

This clinical trial studies the following conditions: Recurrent Nasopharyngeal Cancer, Stage IV Nasopharyngeal Cancer.

What interventions are being tested in trial NCT00305734?

The interventions under investigation include: laboratory biomarker analysis (OTHER), bortezomib (DRUG), gemcitabine hydrochloride (DRUG).

Who is sponsoring clinical trial NCT00305734?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00305734 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

How this trial's enrollment target compares

Where NCT00305734's enrollment target sits among peer trials

50 1195th of 2000 higher than 740 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00305734, the US trial registry maintained by the National Library of Medicine. NCT00305734 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.