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NCT00301860 · ClinicalTrials.gov registry record · NA

Donor Stem Cell Transplant Followed By Donor White Blood Cell Infusions in Treating Young Patients With Hematologic Cancer

A NA study, sponsored by University of California, San Francisco.

Terminated
Registry status
NA
Development phase
8
Enrollment target

NCT00301860 is a NA study that was terminated before completion, run by University of California, San Francisco. The registered enrollment target is 8 participants.

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The verdict

NCT00301860, a NA study, was terminated before completion, sponsored by University of California, San Francisco.

TERMINATED
Registry status
NA
Development phase
8 participants
Enrollment target

Study Summary

RATIONALE: Giving chemotherapy before a donor peripheral blood stem cell transplant helps stop both the growth of cancer cells and the patient's immune system from rejecting the donor's stem cells. When the healthy stem cells from a donor are infused into the patient, they may help the patient's bone marrow make stem cells, red blood cells, white blood cells, and platelets. Sometimes the transplanted cells from a donor can make an immune response against the body's normal cells. Giving chemotherapy, such as fludarabine and melphalan, and antithymocyte globulin before transplant and cyclosporine and methotrexate after transplant may stop this from happening. PURPOSE: This clinical trial is studying how well donor stem cell transplant, using low-dose chemotherapy and antithymocyte globulin, followed by donor white blood cell infusions work in treating young patients with hematologic cancer.

Interventions

  • DRUG fludarabine phosphate
  • BIOLOGICAL filgrastim
  • DRUG cyclosporine
  • BIOLOGICAL anti-thymocyte globulin
  • BIOLOGICAL therapeutic allogeneic lymphocytes

Trial Details

FieldValue
Enrollment Target 8 participants
Start Date 2003-01
Est. Completion 2007-11
Phase NA

What the Registry Record Tells You About NCT00301860

The ClinicalTrials.gov registry entry for NCT00301860 describes a study currently listed as terminated, categorized as NA. The registered enrollment target is 8 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, San Francisco, which has 1,713 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 5 interventions - of which fludarabine phosphate is the first listed.

NCT00301860 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00301860 about?

NCT00301860 is a clinical study titled "Donor Stem Cell Transplant Followed By Donor White Blood Cell Infusions in Treating Young Patients With Hematologic Cancer". RATIONALE: Giving chemotherapy before a donor peripheral blood stem cell transplant helps stop both the growth of cancer cells and the patient's immune system from rejecting the donor's stem cells. When the healthy stem cells from a donor are infused into the patient, they may help the patient's bon...

What is the current status of trial NCT00301860?

This trial is currently terminated. It is a NA study. The enrollment target is 8 participants. The study started on 2003-01. Estimated completion is 2007-11.

What interventions are being tested in trial NCT00301860?

The interventions under investigation include: fludarabine phosphate (DRUG), filgrastim (BIOLOGICAL), cyclosporine (DRUG), anti-thymocyte globulin (BIOLOGICAL), therapeutic allogeneic lymphocytes (BIOLOGICAL).

Who is sponsoring clinical trial NCT00301860?

This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.