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NCT00295854 · ClinicalTrials.gov registry record · Phase 2
Phase II Study Efficacy and Safety of Two Dosing Regimens of MN-001 in Patients With Interstitial Cystitis
A Phase 2 study, sponsored by MediciNova.
- Completed
- Registry status
- Phase 2
- Development phase
- 296
- Enrollment target
NCT00295854: Completed Phase 2 study, sponsored by MediciNova.
NCT00295854 is a Phase 2 study that has completed, run by MediciNova. The registered enrollment target is 296 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (123% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00295854, a Phase 2 study, has completed, sponsored by MediciNova.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 296 participants
- Enrollment target
Study Summary
To evaluate the safety and efficacy of 8 weeks of treatment with MN-001 at 500 mg bid, 500 mg once daily vs. placebo in patients with Interstitial Cystitis.
Primary Outcome
The primary endpoint was the GRA overall change "in their condition" at Week 8. Each patient completed the questionnaire that rated the improvement in their IC symptoms based on responses to the GRA questions. Each question asked the patient to describe the OVERALL CHANGE in pain, urgency, frequency or overall change in their problem compared to the status before taking the study medication. Each parameter was rated on a 7 point scale: markedly worse, moderately worse, mildly worse, same, mildly
Interventions
- DRUG Placebo
- DRUG MN-001
- DRUG MN-001 BID
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 296 participants |
| Start Date | 2005-05 |
| Est. Completion | 2006-10 |
| Phase | Phase 2 |
What the finished NCT00295854 record still lists
NCT00295854 is an interventional study that assigns participants to a tested intervention. The registered 296 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (123% higher).
The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.
NCT00295854 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00295854 about?
NCT00295854 is a clinical study titled "Phase II Study Efficacy and Safety of Two Dosing Regimens of MN-001 in Patients With Interstitial Cystitis". To evaluate the safety and efficacy of 8 weeks of treatment with MN-001 at 500 mg bid, 500 mg once daily vs. placebo in patients with Interstitial Cystitis.
What is the current status of trial NCT00295854?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 296 participants. The study started on 2005-05. Estimated completion is 2006-10.
What interventions are being tested in trial NCT00295854?
The interventions under investigation include: Placebo (DRUG), MN-001 (DRUG), MN-001 BID (DRUG).
Who is sponsoring clinical trial NCT00295854?
This trial is sponsored by MediciNova, which has 17 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00295854's enrollment target sits among peer trials
296 189th of 2000 higher than 1,812 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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