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NCT00290758 · ClinicalTrials.gov registry record · Phase 2
Genistein in Preventing Breast Cancer in Women at High Risk for Breast Cancer
A Phase 2 study, sponsored by National Cancer Institute (NCI).
- Completed
- Registry status
- Phase 2
- Development phase
- 126
- Enrollment target
NCT00290758: Completed Phase 2 study, sponsored by National Cancer Institute (NCI).
NCT00290758 is a Phase 2 study that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 126 participants, roughly in line with the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00290758, a Phase 2 study, has completed, sponsored by National Cancer Institute (NCI).
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 126 participants
- Enrollment target
Study Summary
This randomized phase II trial is studying how well genistein works in preventing breast cancer in women at high risk for breast cancer. Chemoprevention is the use of certain drugs to keep cancer from forming, growing, or coming back. The use of genistein may prevent breast cancer in women at high risk for breast cancer.
Primary Outcome
Breast epithelial tissue samples are used to measure the expression of the cell proliferation marker Ki-67, by counting the percentage of positive MIB-1 immunostained cells, denoted the Ki-67 labeling index. Mean change in the Ki-67 labeling index is assessed from baseline to 6 month follow up.
Interventions
- DRUG placebo
- OTHER laboratory biomarker analysis
- DRUG genistein
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 126 participants |
| Start Date | 2006-01 |
| Est. Completion | 2009-07 |
| Phase | Phase 2 |
What the finished NCT00290758 record still lists
NCT00290758 is an interventional study that assigns participants to a tested intervention. The registered 126 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target.
The record links to 0 conditions, and to 3 interventions - of which placebo is the first listed.
NCT00290758 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00290758 about?
NCT00290758 is a clinical study titled "Genistein in Preventing Breast Cancer in Women at High Risk for Breast Cancer". This randomized phase II trial is studying how well genistein works in preventing breast cancer in women at high risk for breast cancer. Chemoprevention is the use of certain drugs to keep cancer from forming, growing, or coming back. The use of genistein may prevent breast cancer in women at high r...
What is the current status of trial NCT00290758?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 126 participants. The study started on 2006-01. Estimated completion is 2009-07.
What interventions are being tested in trial NCT00290758?
The interventions under investigation include: placebo (DRUG), laboratory biomarker analysis (OTHER), genistein (DRUG).
Who is sponsoring clinical trial NCT00290758?
This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00290758's enrollment target sits among peer trials
126 556th of 2000 higher than 1,443 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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