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NCT00290537 · ClinicalTrials.gov registry record · Phase 2
Phase II Study of ZD6474 in Advanced NSCLC
A Phase 2 study, sponsored by M.D. Anderson Cancer Center.
- Terminated
- Registry status
- Phase 2
- Development phase
- 4
- Enrollment target
NCT00290537: Clinical Trial Phase 2 study, sponsored by M.D. Anderson Cancer Center.
NCT00290537 is a Phase 2 study that was terminated before completion, run by M.D. Anderson Cancer Center. The registered enrollment target is 4 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00290537, a Phase 2 study, was terminated before completion, sponsored by M.D. Anderson Cancer Center.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 4 participants
- Enrollment target
Study Summary
The goal of this clinical research study is to learn how the drug ZD6474 affects the amount of tumor cell death in the body and the amount of blood that can be supplied to the tumor. The safety of ZD6474 alone and when given with chemotherapy will be studied. In addition, the side effects and response to this treatment will also be studied.
Primary Outcome
Evaluate the response rate in patients receiving monotherapy with ZD6474 compared to ZD6474 plus carboplatin plus paclitaxel. No formal comparisons could be made and no conclusions drawn because of small numbers in the treatment groups; a result of an inability to fulfil the recruitment target.
Interventions
- DRUG Carboplatin
- DRUG Paclitaxel
- DRUG ZD6474
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4 participants |
| Start Date | 2006-01 |
| Est. Completion | 2008-04 |
| Phase | Phase 2 |
Why NCT00290537 stopped before completion
NCT00290537 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 3 interventions - of which Carboplatin is the first listed.
NCT00290537 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00290537 about?
NCT00290537 is a clinical study titled "Phase II Study of ZD6474 in Advanced NSCLC". The goal of this clinical research study is to learn how the drug ZD6474 affects the amount of tumor cell death in the body and the amount of blood that can be supplied to the tumor. The safety of ZD6474 alone and when given with chemotherapy will be studied. In addition, the side effects and respon...
What is the current status of trial NCT00290537?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 4 participants. The study started on 2006-01. Estimated completion is 2008-04.
What interventions are being tested in trial NCT00290537?
The interventions under investigation include: Carboplatin (DRUG), Paclitaxel (DRUG), ZD6474 (DRUG).
Who is sponsoring clinical trial NCT00290537?
This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00290537's enrollment target sits among peer trials
4 2001st of 2000 the lowest of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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