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NCT00285207 · ClinicalTrials.gov registry record · Phase 2

Safety and Efficacy of A-007 Topical Gel in the Treatment of High-Grade Squamous Intraepithelial Lesions (HSIL) of the Cervix

A Phase 2 study of Cervical Intraepithelial Neoplasia and Uterine Cervical Dysplasia, sponsored by Tigris Pharmaceuticals.

Completed
Registry status
Phase 2
Development phase
147
Enrollment target
20
Study locations

NCT00285207 is a Phase 2 study of Cervical Intraepithelial Neoplasia and Uterine Cervical Dysplasia that has completed, run by Tigris Pharmaceuticals. The registered enrollment target is 147 participants, below the 246-participant average among 6 other Cervical Intraepithelial Neoplasia trials with a reported enrollment target (40% lower). The trial reports 20 study locations across 11 states.

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The verdict

NCT00285207, a Phase 2 study of Cervical Intraepithelial Neoplasia and Uterine Cervical Dysplasia, has completed, sponsored by Tigris Pharmaceuticals.

COMPLETED
Registry status
Phase 2
Development phase
147 participants
Enrollment target
20
Study locations

Study Summary

A-007 is an investigational therapy which may be effective in the treatment of pre-cancerous cervical dysplasia (abnormal cell growth). The purpose of this study is to evaluate the safety and efficacy of A-007, when used to treat high-grade cervical dysplasia.

Interventions

  • DRUG placebo
  • DRUG A007

Study Locations (20)

California

  • Northern California Research Corp - Carmichael
  • Arrowhead Regional Medical Center - Colton
  • Robin Black OGNP - Costa Mesa
  • IGO Medical Group of San Diego - San Diego

Florida

  • Visions Clinical Research - Boynton Beach
  • Global OB/GYN Centers of Florida - Pembroke Pines
  • Physician Care Clinical Research, LLC. - Sarasota
  • OB/GYN Specialists of the Palm Beaches - West Palm Beach

Arizona

  • Hope Research Institute, LLC - Phoenix
  • Visions Clinical Research-Tucson - Tucson

Georgia

  • Mount Vernon Clinical Research, LLC - Atlanta
  • Medical College of Georgia - Augusta

New York

  • New York Downtown Hospital - New York
  • Jacobi Medical Center - The Bronx

Alabama

  • University of Alabama Highlands, Dept. of OB/GYN - Birmingham

Connecticut

  • Coastal Connecticut Research, LLC - New London

District of Columbia

  • Washington Hospital Center - Washington D.C.

Trial Details

FieldValue
Enrollment Target 147 participants
Start Date 2006-01
Est. Completion 2008-06
Phase Phase 2

Sponsor

Tigris Pharmaceuticals

3 total trials

What the Registry Record Tells You About NCT00285207

The ClinicalTrials.gov registry entry for NCT00285207 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 147 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 246-participant average among 6 other Cervical Intraepithelial Neoplasia trials with a reported enrollment target (40% lower). The listed sponsor is Tigris Pharmaceuticals, which has 3 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Cervical Intraepithelial Neoplasia appearing as the primary indexed condition, and to 2 interventions - of which placebo is the first listed.

NCT00285207 reports 20 study locations spanning 11 distinct geographic areas - top geographies include California, Florida, Arizona.

Frequently Asked Questions

What is clinical trial NCT00285207 about?

NCT00285207 is a clinical study titled "Safety and Efficacy of A-007 Topical Gel in the Treatment of High-Grade Squamous Intraepithelial Lesions (HSIL) of the Cervix". A-007 is an investigational therapy which may be effective in the treatment of pre-cancerous cervical dysplasia (abnormal cell growth). The purpose of this study is to evaluate the safety and efficacy of A-007, when used to treat high-grade cervical dysplasia.

What is the current status of trial NCT00285207?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 147 participants. The study started on 2006-01. Estimated completion is 2008-06.

What conditions does trial NCT00285207 study?

This clinical trial studies the following conditions: Cervical Intraepithelial Neoplasia, Uterine Cervical Dysplasia.

What interventions are being tested in trial NCT00285207?

The interventions under investigation include: placebo (DRUG), A007 (DRUG).

Who is sponsoring clinical trial NCT00285207?

This trial is sponsored by Tigris Pharmaceuticals, which has 3 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00285207 being conducted?

This trial has 20 study locations across Alabama, Arizona, California, Connecticut, District of Columbia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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