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NCT00280280 · ClinicalTrials.gov registry record · Phase 1
Botox vs. Baclofen for Upper Limb Spasticity
A Phase 1 study, sponsored by Vanderbilt University.
- Terminated
- Registry status
- Phase 1
- Development phase
- 8
- Enrollment target
NCT00280280: Clinical Trial Phase 1 study, sponsored by Vanderbilt University.
NCT00280280 is a Phase 1 study that was terminated before completion, run by Vanderbilt University. The registered enrollment target is 8 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (87% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00280280, a Phase 1 study, was terminated before completion, sponsored by Vanderbilt University.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 8 participants
- Enrollment target
Study Summary
The purposes of this pilot study are to evaluate the safety and efficacy of Botox® compared to the safety and efficacy of oral baclofen in reducing muscle tone-related disability resulting from neurological damage or a stable neurological disorder and to evaluate drug-therapy tolerance.
Interventions
- DRUG intramuscular Botox versus oral baclofen
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 8 participants |
| Start Date | 2006-02 |
| Est. Completion | 2009-02 |
| Phase | Phase 1 |
Why NCT00280280 stopped before completion
NCT00280280 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (87% lower).
The record links to 0 conditions, and to 1 intervention - of which intramuscular Botox versus oral baclofen is the first listed.
NCT00280280 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00280280 about?
NCT00280280 is a clinical study titled "Botox vs. Baclofen for Upper Limb Spasticity". The purposes of this pilot study are to evaluate the safety and efficacy of Botox® compared to the safety and efficacy of oral baclofen in reducing muscle tone-related disability resulting from neurological damage or a stable neurological disorder and to evaluate drug-therapy tolerance.
What is the current status of trial NCT00280280?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 8 participants. The study started on 2006-02. Estimated completion is 2009-02.
What interventions are being tested in trial NCT00280280?
The interventions under investigation include: intramuscular Botox versus oral baclofen (DRUG).
Who is sponsoring clinical trial NCT00280280?
This trial is sponsored by Vanderbilt University, which has 430 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00280280's enrollment target sits among peer trials
8 1959th of 2000 higher than 29 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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