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NCT00277290 · ClinicalTrials.gov registry record · Phase 2
Study of XL999 in Patients With Previously Treated Ovarian Cancer
A Phase 2 study, sponsored by Symphony Evolution.
- Terminated
- Registry status
- Phase 2
- Development phase
- 24
- Enrollment target
NCT00277290: Clinical Trial Phase 2 study, sponsored by Symphony Evolution.
NCT00277290 is a Phase 2 study that was terminated before completion, run by Symphony Evolution. The registered enrollment target is 24 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (82% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00277290, a Phase 2 study, was terminated before completion, sponsored by Symphony Evolution.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 24 participants
- Enrollment target
Study Summary
This clinical trial is being conducted at multiple sites to evaluate the activity, safety, and tolerability of XL999 when given weekly to patients with ovarian cancer that has previously been treated with platinum-based chemotherapy. XL999 is a small molecule inhibitor of multiple kinases including VEGFR, PDGFR, FGFR, FLT-3, and Src, which are involved in tumor cell growth, formation of new blood vessels (angiogenesis), and metastasis.
Interventions
- DRUG XL999
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2006-01 |
| Est. Completion | 2006-11 |
| Phase | Phase 2 |
Why NCT00277290 stopped before completion
NCT00277290 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (82% lower).
The record links to 0 conditions, and to 1 intervention - of which XL999 is the first listed.
NCT00277290 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00277290 about?
NCT00277290 is a clinical study titled "Study of XL999 in Patients With Previously Treated Ovarian Cancer". This clinical trial is being conducted at multiple sites to evaluate the activity, safety, and tolerability of XL999 when given weekly to patients with ovarian cancer that has previously been treated with platinum-based chemotherapy. XL999 is a small molecule inhibitor of multiple kinases including ...
What is the current status of trial NCT00277290?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 24 participants. The study started on 2006-01. Estimated completion is 2006-11.
What interventions are being tested in trial NCT00277290?
The interventions under investigation include: XL999 (DRUG).
Who is sponsoring clinical trial NCT00277290?
This trial is sponsored by Symphony Evolution, which has 10 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00277290's enrollment target sits among peer trials
24 1756th of 2000 higher than 217 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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