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NCT00275249 · ClinicalTrials.gov registry record · NA

Evolution of Analgesic Tolerance With Opioids

A NA study, sponsored by University of California, San Francisco.

Completed
Registry status
NA
Development phase
60
Enrollment target

NCT00275249: Completed NA study, sponsored by University of California, San Francisco.

NCT00275249 is a NA study that has completed, run by University of California, San Francisco. The registered enrollment target is 60 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00275249, a NA study, has completed, sponsored by University of California, San Francisco.

COMPLETED
Registry status
NA
Development phase
60 participants
Enrollment target

Study Summary

The purpose of this study is to determine the extent to which analgesic tolerance develops in chronic pain patients who are either started on opioids or who receive an increase in pre-study opioid dose level and then observed during long-term (20 weeks) stable opioid therapy. In addition to clinical measures of relief of ongoing chronic pain, estimation of tolerance development will be supplemented by periodic assessment of the anti-nociceptive effects of opioids using the brief thermal sensitization model.

Interventions

  • DRUG levorphanol

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2001-03
Est. Completion 2005-12
Phase NA

What the finished NCT00275249 record still lists

NCT00275249 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).

The record links to 0 conditions, and to 1 intervention - of which levorphanol is the first listed.

NCT00275249 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00275249 about?

NCT00275249 is a clinical study titled "Evolution of Analgesic Tolerance With Opioids". The purpose of this study is to determine the extent to which analgesic tolerance develops in chronic pain patients who are either started on opioids or who receive an increase in pre-study opioid dose level and then observed during long-term (20 weeks) stable opioid therapy. In addition to clinical...

What is the current status of trial NCT00275249?

This trial is currently completed. It is a NA study. The enrollment target is 60 participants. The study started on 2001-03. Estimated completion is 2005-12.

What interventions are being tested in trial NCT00275249?

The interventions under investigation include: levorphanol (DRUG).

Who is sponsoring clinical trial NCT00275249?

This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00275249's enrollment target sits among peer trials

60 1164th of 2000 higher than 745 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00275249, the US trial registry maintained by the National Library of Medicine. NCT00275249 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.