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NCT00275002 · ClinicalTrials.gov registry record · Phase 2

O6-Benzylguanine and Temozolomide in Treating Young Patients With Recurrent or Progressive Gliomas or Brain Stem Tumors

A Phase 2 study, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 2
Development phase
41
Enrollment target

NCT00275002: Completed Phase 2 study, sponsored by National Cancer Institute (NCI).

NCT00275002 is a Phase 2 study that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 41 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00275002, a Phase 2 study, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 2
Development phase
41 participants
Enrollment target

Study Summary

This phase II trial is studying how well giving O6-benzylguanine together with temozolomide works in treating young patients with recurrent or progressive gliomas or brain stem tumors. Drugs used in chemotherapy, such as O6-benzylguanine and temozolomide , work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. O6-benzylguanine may help temozolomide work better by making tumor cells more sensitive to the drug. Giving more than one drug (combination chemotherapy) may kill more tumor cells.

Interventions

  • DRUG O6-benzylguanine
  • DRUG temozolomide

Trial Details

FieldValue
Enrollment Target 41 participants
Start Date 2006-02
Est. Completion 2010-12
Phase Phase 2

Sponsor

National Cancer Institute (NCI)

3,257 total trials

What the Registry Record Tells You About NCT00275002

The ClinicalTrials.gov registry entry for NCT00275002 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 41 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which O6-benzylguanine is the first listed.

NCT00275002 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00275002 about?

NCT00275002 is a clinical study titled "O6-Benzylguanine and Temozolomide in Treating Young Patients With Recurrent or Progressive Gliomas or Brain Stem Tumors". This phase II trial is studying how well giving O6-benzylguanine together with temozolomide works in treating young patients with recurrent or progressive gliomas or brain stem tumors. Drugs used in chemotherapy, such as O6-benzylguanine and temozolomide , work in different ways to stop the growth o...

What is the current status of trial NCT00275002?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 41 participants. The study started on 2006-02. Estimated completion is 2010-12.

What interventions are being tested in trial NCT00275002?

The interventions under investigation include: O6-benzylguanine (DRUG), temozolomide (DRUG).

Who is sponsoring clinical trial NCT00275002?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.