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NCT00273936 · ClinicalTrials.gov registry record · Phase 1

Trial of AVN-944 in Patients With Advanced Hematologic Malignancies

A Phase 1 study, sponsored by Vertex Pharmaceuticals Incorporated.

Completed
Registry status
Phase 1
Development phase
72
Enrollment target

NCT00273936: Completed Phase 1 study, sponsored by Vertex Pharmaceuticals Incorporated.

NCT00273936 is a Phase 1 study that has completed, run by Vertex Pharmaceuticals Incorporated. The registered enrollment target is 72 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (20% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00273936, a Phase 1 study, has completed, sponsored by Vertex Pharmaceuticals Incorporated.

COMPLETED
Registry status
Phase 1
Development phase
72 participants
Enrollment target

Study Summary

The purpose of this study is to determine the safety and maximum tolerated dose, pharmacokinetics, and anti-neoplastic response of AVN-944 in patients with advanced hematologic malignancies.

Interventions

  • DRUG AVN-944 capsules for oral administration

Trial Details

FieldValue
Enrollment Target 72 participants
Start Date 2006-01
Phase Phase 1
Vertex Pharmaceuticals Incorporated

191 total trials

What the finished NCT00273936 record still lists

NCT00273936 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 72 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (20% higher).

The record links to 0 conditions, and to 1 intervention - of which AVN-944 capsules for oral administration is the first listed.

NCT00273936 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00273936 about?

NCT00273936 is a clinical study titled "Trial of AVN-944 in Patients With Advanced Hematologic Malignancies". The purpose of this study is to determine the safety and maximum tolerated dose, pharmacokinetics, and anti-neoplastic response of AVN-944 in patients with advanced hematologic malignancies.

What is the current status of trial NCT00273936?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 72 participants. The study started on 2006-01.

What interventions are being tested in trial NCT00273936?

The interventions under investigation include: AVN-944 capsules for oral administration (DRUG).

Who is sponsoring clinical trial NCT00273936?

This trial is sponsored by Vertex Pharmaceuticals Incorporated, which has 191 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00273936's enrollment target sits among peer trials

72 736th of 2000 higher than 1,254 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00273936, the US trial registry maintained by the National Library of Medicine. NCT00273936 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.