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NCT00268905 · ClinicalTrials.gov registry record · Phase 1
A Dose-Finding Study of E7389 in Combination With Carboplatin in Patients With Solid Tumors
A Phase 1 study, sponsored by Eisai.
- Completed
- Registry status
- Phase 1
- Development phase
- 64
- Enrollment target
NCT00268905: Completed Phase 1 study, sponsored by Eisai.
NCT00268905 is a Phase 1 study that has completed, run by Eisai. The registered enrollment target is 64 participants, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00268905, a Phase 1 study, has completed, sponsored by Eisai.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 64 participants
- Enrollment target
Study Summary
The purpose of this study is to determine the maximum tolerated dose (MTD) and to explore the safety and anti-tumor activity of E7389 in combination with carboplatin in patients with advanced solid tumors.
Primary Outcome
MTD was established by summarizing the number and percent of subject with dose- limiting toxicities (DLTs) for the first cycle.
Interventions
- DRUG E7389 + carboplatin AUC 5
- DRUG E7389 + carboplatin AUC 6
- DRUG E7389+carboplatin AUC 6
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 64 participants |
| Start Date | 2006-10 |
| Phase | Phase 1 |
What the finished NCT00268905 record still lists
NCT00268905 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 64 participants, a relatively small participant target, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target.
The record links to 0 conditions, and to 3 interventions - of which E7389 + carboplatin AUC 5 is the first listed.
NCT00268905 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00268905 about?
NCT00268905 is a clinical study titled "A Dose-Finding Study of E7389 in Combination With Carboplatin in Patients With Solid Tumors". The purpose of this study is to determine the maximum tolerated dose (MTD) and to explore the safety and anti-tumor activity of E7389 in combination with carboplatin in patients with advanced solid tumors.
What is the current status of trial NCT00268905?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 64 participants. The study started on 2006-10.
What interventions are being tested in trial NCT00268905?
The interventions under investigation include: E7389 + carboplatin AUC 5 (DRUG), E7389 + carboplatin AUC 6 (DRUG), E7389+carboplatin AUC 6 (DRUG).
Who is sponsoring clinical trial NCT00268905?
This trial is sponsored by Eisai, which has 287 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00268905's enrollment target sits among peer trials
64 808th of 2000 higher than 1,181 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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