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NCT00268853 · ClinicalTrials.gov registry record · Phase 2
A Trial in Patients With Diffuse Large-B-cell Lymphoma Comparing Pixantrone Against Doxorubicin
A Phase 2 study, sponsored by CTI BioPharma.
- Completed
- Registry status
- Phase 2
- Development phase
- 124
- Enrollment target
NCT00268853: Completed Phase 2 study, sponsored by CTI BioPharma.
NCT00268853 is a Phase 2 study that has completed, run by CTI BioPharma. The registered enrollment target is 124 participants, roughly in line with the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00268853, a Phase 2 study, has completed, sponsored by CTI BioPharma.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 124 participants
- Enrollment target
Study Summary
The purpose of this study is to compare the standard CHOP-R regimen of Cyclophosphamide, Doxorubicin, Vincristine, Prednisone, and Rituximab to CPOP-R (same regimen, but substituting Doxorubicin with Pixantrone). The objective is to show that CPOP-R is not inferior to CHOP-R.
Interventions
- DRUG CPOP-R
- DRUG CHOP-R
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 124 participants |
| Start Date | 2005-11 |
| Est. Completion | 2012-05 |
| Phase | Phase 2 |
What the finished NCT00268853 record still lists
NCT00268853 is an interventional study that assigns participants to a tested intervention. The registered 124 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target.
The record links to 0 conditions, and to 2 interventions - of which CPOP-R is the first listed.
NCT00268853 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00268853 about?
NCT00268853 is a clinical study titled "A Trial in Patients With Diffuse Large-B-cell Lymphoma Comparing Pixantrone Against Doxorubicin". The purpose of this study is to compare the standard CHOP-R regimen of Cyclophosphamide, Doxorubicin, Vincristine, Prednisone, and Rituximab to CPOP-R (same regimen, but substituting Doxorubicin with Pixantrone). The objective is to show that CPOP-R is not inferior to CHOP-R.
What is the current status of trial NCT00268853?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 124 participants. The study started on 2005-11. Estimated completion is 2012-05.
What interventions are being tested in trial NCT00268853?
The interventions under investigation include: CPOP-R (DRUG), CHOP-R (DRUG).
Who is sponsoring clinical trial NCT00268853?
This trial is sponsored by CTI BioPharma, which has 28 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00268853's enrollment target sits among peer trials
124 564th of 2000 higher than 1,437 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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