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NCT00266903 · ClinicalTrials.gov registry record
Eisenmenger's Syndrome in Adults With CHD
A clinical trial, sponsored by Children's Healthcare of Atlanta.
- Completed
- Registry status
- 48
- Enrollment target
NCT00266903: Completed study, sponsored by Children's Healthcare of Atlanta.
NCT00266903 is a clinical trial that has completed, run by Children's Healthcare of Atlanta. The registered enrollment target is 48 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00266903 has completed, sponsored by Children's Healthcare of Atlanta.
- COMPLETED
- Registry status
- 48 participants
- Enrollment target
Study Summary
Review the outcome of treatment with endothelin receptor antagonists (bosentan or sitaxsetan) alone or in combination with Sildenafil (a PDE-5 inhibitor) in adult patients with pulmonary hypertension due to congenital heart disease.
Primary Outcome
Our study demonstrates that endothelin receptor blockers can be used to improve exercise tolerance, oxygenation, and functional status in adults with Eisenmenger syndrome without adverse effects. The role of newer treatment modalities such as prostacyclins, PDE inhibitors, and nitric oxide remain promising and their role needs to be investigated to help improve quality of life and life expectancy in these patients.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 1996-01 |
| Est. Completion | 2008-01 |
What the finished NCT00266903 record still lists
NCT00266903 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 48 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT00266903 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00266903 about?
NCT00266903 is a clinical study titled "Eisenmenger's Syndrome in Adults With CHD". Review the outcome of treatment with endothelin receptor antagonists (bosentan or sitaxsetan) alone or in combination with Sildenafil (a PDE-5 inhibitor) in adult patients with pulmonary hypertension due to congenital heart disease.
What is the current status of trial NCT00266903?
This trial is currently completed. The enrollment target is 48 participants. The study started on 1996-01. Estimated completion is 2008-01.
Who is sponsoring clinical trial NCT00266903?
This trial is sponsored by Children's Healthcare of Atlanta, which has 80 total clinical trials registered on ClinicalTrials.gov.
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