Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00266253 · ClinicalTrials.gov registry record · Phase 2

A Study of GK Activator (2) in Patients With Type 2 Diabetes Mellitus Treated With a Stable Dose of Metformin

A Phase 2 study, sponsored by Hoffmann-La Roche.

Completed
Registry status
Phase 2
Development phase
220
Enrollment target

NCT00266253 is a Phase 2 study that has completed, run by Hoffmann-La Roche. The registered enrollment target is 220 participants.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00266253, a Phase 2 study, has completed, sponsored by Hoffmann-La Roche.

COMPLETED
Registry status
Phase 2
Development phase
220 participants
Enrollment target

Study Summary

This study will evaluate the efficacy, safety, tolerability, and pharmacokinetics of GK Activator (2) in combination with metformin, compared to that of placebo (metformin monotherapy), in patients with type 2 diabetes mellitus. Patients will continue on their stable dose of metformin and will be randomized to receive either GK Activator (2) or placebo. The anticipated time on study treatment is less than 3 months, and the target sample size is 100-500 individuals.

Interventions

  • DRUG Metformin
  • DRUG GK Activator (2)

Trial Details

FieldValue
Enrollment Target 220 participants
Start Date 2005-11
Est. Completion 2007-03
Phase Phase 2

Sponsor

Hoffmann-La Roche

909 total trials

What the Registry Record Tells You About NCT00266253

The ClinicalTrials.gov registry entry for NCT00266253 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 220 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Hoffmann-La Roche, which has 909 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Metformin is the first listed.

NCT00266253 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00266253 about?

NCT00266253 is a clinical study titled "A Study of GK Activator (2) in Patients With Type 2 Diabetes Mellitus Treated With a Stable Dose of Metformin". This study will evaluate the efficacy, safety, tolerability, and pharmacokinetics of GK Activator (2) in combination with metformin, compared to that of placebo (metformin monotherapy), in patients with type 2 diabetes mellitus. Patients will continue on their stable dose of metformin and will be ra...

What is the current status of trial NCT00266253?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 220 participants. The study started on 2005-11. Estimated completion is 2007-03.

What interventions are being tested in trial NCT00266253?

The interventions under investigation include: Metformin (DRUG), GK Activator (2) (DRUG).

Who is sponsoring clinical trial NCT00266253?

This trial is sponsored by Hoffmann-La Roche, which has 909 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.