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NCT00266058 · ClinicalTrials.gov registry record · Phase 1

Drug Interaction Study Between Antimalarial and Anti-HIV Medications

A Phase 1 study, sponsored by University of California, San Francisco.

Completed
Registry status
Phase 1
Development phase
33
Enrollment target

NCT00266058 is a Phase 1 study that has completed, run by University of California, San Francisco. The registered enrollment target is 33 participants.

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The verdict

NCT00266058, a Phase 1 study, has completed, sponsored by University of California, San Francisco.

COMPLETED
Registry status
Phase 1
Development phase
33 participants
Enrollment target

Study Summary

The purpose of this study is to find out whether taking certain anti-HIV medicines with certain antimalarial medicines affects the amount of the medicines in the blood. The study medicines that will be used are artemether/lumefantrine (antimalarial medication) and lopinavir/ritonavir or efavirenz (anti-HIV medications). Artemether/lumefantrine is not approved by the United States Food and Drug Administration (FDA) but is recommended as standard of care medical treatment for malaria in Africa and Asia. Lopinavir/ritonavir and efavirenz are approved by the FDA. Artemether/lumefantrine and lopinavir/ritonavir or efavirenz may need to be used together to treat children in Africa and Asia. We seek to learn about whether or not the use of these medicines together results in a change in blood levels of any of these medicines. The information obtained from this study will help doctors to provide a better treatment to children and adults with malaria and HIV.

Interventions

  • DRUG Lopinavir/Ritonavir, Efavirenz, Artemether/lumefantrine

Trial Details

FieldValue
Enrollment Target 33 participants
Start Date 2005-12
Est. Completion 2010-11
Phase Phase 1

What the Registry Record Tells You About NCT00266058

The ClinicalTrials.gov registry entry for NCT00266058 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 33 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, San Francisco, which has 1,713 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Lopinavir/Ritonavir, Efavirenz, Artemether/lumefantrine is the first listed.

NCT00266058 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00266058 about?

NCT00266058 is a clinical study titled "Drug Interaction Study Between Antimalarial and Anti-HIV Medications". The purpose of this study is to find out whether taking certain anti-HIV medicines with certain antimalarial medicines affects the amount of the medicines in the blood. The study medicines that will be used are artemether/lumefantrine (antimalarial medication) and lopinavir/ritonavir or efavirenz (...

What is the current status of trial NCT00266058?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 33 participants. The study started on 2005-12. Estimated completion is 2010-11.

What interventions are being tested in trial NCT00266058?

The interventions under investigation include: Lopinavir/Ritonavir, Efavirenz, Artemether/lumefantrine (DRUG).

Who is sponsoring clinical trial NCT00266058?

This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.