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NCT00260325 · ClinicalTrials.gov registry record · Phase 4
Effect of Valdecoxib Pretreatment on Pain and Secondary Hyperalgesia in Healthy Volunteers
A Phase 4 study, sponsored by Penn State University.
- Completed
- Registry status
- Phase 4
- Development phase
- 20
- Enrollment target
NCT00260325: Completed Phase 4 study, sponsored by Penn State University.
NCT00260325 is a Phase 4 study that has completed, run by Penn State University. The registered enrollment target is 20 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00260325, a Phase 4 study, has completed, sponsored by Penn State University.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 20 participants
- Enrollment target
Study Summary
Tis study was designed to test the hypothesis that pretreatment with valdecoxib, prior to injury could reduce or prevent the development of secondary hyperalgesia around the area of primary injury. A heat/capsaicin model of induced hyperalgesia was tested in healthy volunteers in a randomized, double blind, cross-over trial of a single dose of 40 mg vadecoxib versus control. Subjects rated pain intesnsity and unpleasantness following heat stimulation of the forearm, the area of hyperalgesia was also mapped over the course of the experiment.
Interventions
- DRUG valdecoxib
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2004-08 |
| Est. Completion | 2006-04 |
| Phase | Phase 4 |
What the finished NCT00260325 record still lists
NCT00260325 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 1 intervention - of which valdecoxib is the first listed.
NCT00260325 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00260325 about?
NCT00260325 is a clinical study titled "Effect of Valdecoxib Pretreatment on Pain and Secondary Hyperalgesia in Healthy Volunteers". Tis study was designed to test the hypothesis that pretreatment with valdecoxib, prior to injury could reduce or prevent the development of secondary hyperalgesia around the area of primary injury. A heat/capsaicin model of induced hyperalgesia was tested in healthy volunteers in a randomized, doubl...
What is the current status of trial NCT00260325?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 20 participants. The study started on 2004-08. Estimated completion is 2006-04.
What interventions are being tested in trial NCT00260325?
The interventions under investigation include: valdecoxib (DRUG).
Who is sponsoring clinical trial NCT00260325?
This trial is sponsored by Penn State University, which has 219 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00260325's enrollment target sits among peer trials
20 1753rd of 2000 higher than 167 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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