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NCT00252239 · ClinicalTrials.gov registry record · Phase 2
Study of Tenecteplase (TNK) in Acute Ischemic Stroke (TNK-S2B)
A Phase 2 study, sponsored by University of Virginia.
- Terminated
- Registry status
- Phase 2
- Development phase
- 112
- Enrollment target
NCT00252239: Clinical Trial Phase 2 study, sponsored by University of Virginia.
NCT00252239 is a Phase 2 study that was terminated before completion, run by University of Virginia. The registered enrollment target is 112 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (16% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00252239, a Phase 2 study, was terminated before completion, sponsored by University of Virginia.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 112 participants
- Enrollment target
Study Summary
The purpose of this study is to determine which of 3 different doses of tenecteplase (TNK) is better for treating stroke patients and if TNK offers an advantage over currently available treatment with tissue plasminogen activator (tPA).
Primary Outcome
The scale range is from 0 (perfect health without symptoms) to 6 (death). Percentage of participants with Modified Rankin Score \>=4 are reported.
Interventions
- DRUG tenecteplase
- DRUG tissue plasminogen activator, tPA
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 112 participants |
| Start Date | 2005-11 |
| Est. Completion | 2009-09 |
| Phase | Phase 2 |
Why NCT00252239 stopped before completion
NCT00252239 is an interventional study that assigns participants to a tested intervention. The registered 112 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (16% lower).
The record links to 0 conditions, and to 2 interventions - of which tenecteplase is the first listed.
NCT00252239 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00252239 about?
NCT00252239 is a clinical study titled "Study of Tenecteplase (TNK) in Acute Ischemic Stroke (TNK-S2B)". The purpose of this study is to determine which of 3 different doses of tenecteplase (TNK) is better for treating stroke patients and if TNK offers an advantage over currently available treatment with tissue plasminogen activator (tPA).
What is the current status of trial NCT00252239?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 112 participants. The study started on 2005-11. Estimated completion is 2009-09.
What interventions are being tested in trial NCT00252239?
The interventions under investigation include: tenecteplase (DRUG), tissue plasminogen activator, tPA (DRUG).
Who is sponsoring clinical trial NCT00252239?
This trial is sponsored by University of Virginia, which has 449 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00252239's enrollment target sits among peer trials
112 631st of 2000 higher than 1,369 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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