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NCT00248326 · ClinicalTrials.gov registry record
The Genetic Basis of Atrial Fibrillation (AF)
A clinical trial, sponsored by University of Pittsburgh.
- Completed
- Registry status
- 50
- Enrollment target
NCT00248326: Completed study, sponsored by University of Pittsburgh.
NCT00248326 is a clinical trial that has completed, run by University of Pittsburgh. The registered enrollment target is 50 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00248326 has completed, sponsored by University of Pittsburgh.
- COMPLETED
- Registry status
- 50 participants
- Enrollment target
Study Summary
The investigators' goal with this research is to: 1. Establish a clinical database and a DNA bank for 1000 individuals with AF and 1000 individuals without AF. 2. Directly test the hypothesis that known functional polymorphisms in the coding sequences and the promoter regions of cardiac genes (ion channels and genes known to affect survival in the setting of left ventricular dysfunction) predispose individuals to AF. Over the past decade, advancing techniques and technologies for gene characterization have yielded significant clues as to the molecular mechanism of certain human heart rhythm disorders. The role of ion channel polymorphisms in subjects with AF is unknown. Similarly, it is also not known whether polymorphisms in other genes have an impact on the risk of AF. The ability to characterize genomic "at-risk" profiles would have many potential benefits for patient care. Paramount among these is: 1. Increased oversight or intervention of at-risk subjects, which might prevent unnecessary morbidity and mortality due to AF. 2. Further insight into the pathogenesis of AF, which may lead to preventative or curative therapies.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2005-01 |
| Est. Completion | 2010-01 |
What the finished NCT00248326 record still lists
NCT00248326 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 50 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT00248326 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00248326 about?
NCT00248326 is a clinical study titled "The Genetic Basis of Atrial Fibrillation (AF)". The investigators' goal with this research is to: 1. Establish a clinical database and a DNA bank for 1000 individuals with AF and 1000 individuals without AF. 2. Directly test the hypothesis that known functional polymorphisms in the coding sequences and the promoter regions of cardiac genes (ion ...
What is the current status of trial NCT00248326?
This trial is currently completed. The enrollment target is 50 participants. The study started on 2005-01. Estimated completion is 2010-01.
Who is sponsoring clinical trial NCT00248326?
This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.
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