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NCT00241839 · ClinicalTrials.gov registry record · Phase 3
Uric Acid and Hypertension in African Americans
A Phase 3 study, sponsored by University of Florida.
- Completed
- Registry status
- Phase 3
- Development phase
- 150
- Enrollment target
NCT00241839: Completed Phase 3 study, sponsored by University of Florida.
NCT00241839 is a Phase 3 study that has completed, run by University of Florida. The registered enrollment target is 150 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (81% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00241839, a Phase 3 study, has completed, sponsored by University of Florida.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 150 participants
- Enrollment target
Study Summary
This study will test the hypothesis that the administration of a xanthine oxidase inhibitor (allopurinol) will prevent thiazide-induced hyperuricemia, which will result in better blood pressure (BP) control in African Americans.
Primary Outcome
The Diastolic BP was taken at Baseline and after 8-10 weeks of treatment or placebo while on chlorthalidone and potassium chloride. The blood pressure was measured according to "Shared Care" protocol: 15 minutes of quiet, undisturbed rest with three BP measurements obtained subsequently at 5 minute intervals. The mean of the second and third reading was the value used for analysis for both the Baseline measurement and the measurement after 8 - 10 weeks of treatment. The dependent variable is ba
Interventions
- DRUG Placebo
- DRUG Chlorthalidone
- DRUG Allopurinol
- DRUG Potassium chloride
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2005-08 |
| Est. Completion | 2011-05 |
| Phase | Phase 3 |
What the finished NCT00241839 record still lists
NCT00241839 is an interventional study that assigns participants to a tested intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (81% lower).
The record links to 0 conditions, and to 4 interventions - of which Placebo is the first listed.
NCT00241839 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00241839 about?
NCT00241839 is a clinical study titled "Uric Acid and Hypertension in African Americans". This study will test the hypothesis that the administration of a xanthine oxidase inhibitor (allopurinol) will prevent thiazide-induced hyperuricemia, which will result in better blood pressure (BP) control in African Americans.
What is the current status of trial NCT00241839?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 150 participants. The study started on 2005-08. Estimated completion is 2011-05.
What interventions are being tested in trial NCT00241839?
The interventions under investigation include: Placebo (DRUG), Chlorthalidone (DRUG), Allopurinol (DRUG), Potassium chloride (DRUG).
Who is sponsoring clinical trial NCT00241839?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00241839's enrollment target sits among peer trials
150 1519th of 2000 higher than 455 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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