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NCT00238394 · ClinicalTrials.gov registry record · Phase 2

Cediranib Maleate in Treating Patients With Locally Advanced or Metastatic Liver Cancer

A Phase 2 study, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 2
Development phase
44
Enrollment target

NCT00238394: Completed Phase 2 study, sponsored by National Cancer Institute (NCI).

NCT00238394 is a Phase 2 study that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 44 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (67% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT00238394, a Phase 2 study, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 2
Development phase
44 participants
Enrollment target

Study Summary

AZD2171 (cediranib maleate) may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. This phase II trial is studying how well AZD2171 works in treating patients with locally advanced or metastatic liver cancer.

Primary Outcome

Will be estimated by the proportion of patients surviving more than 6 months. Ninety-five percent confidence intervals for the true success proportion will be calculated according to the approach of Duffy and Santner.

Interventions

  • OTHER laboratory biomarker analysis
  • DRUG cediranib maleate

Trial Details

FieldValue
Enrollment Target 44 participants
Start Date 2005-12
Phase Phase 2
National Cancer Institute (NCI)

3,257 total trials

What the finished NCT00238394 record still lists

NCT00238394 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 44 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (67% lower).

The record links to 0 conditions, and to 2 interventions - of which laboratory biomarker analysis is the first listed.

NCT00238394 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00238394 about?

NCT00238394 is a clinical study titled "Cediranib Maleate in Treating Patients With Locally Advanced or Metastatic Liver Cancer". AZD2171 (cediranib maleate) may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. This phase II trial is studying how well AZD2171 works in treating patients with locally advanced or metastatic liver cancer.

What is the current status of trial NCT00238394?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 44 participants. The study started on 2005-12.

What interventions are being tested in trial NCT00238394?

The interventions under investigation include: laboratory biomarker analysis (OTHER), cediranib maleate (DRUG).

Who is sponsoring clinical trial NCT00238394?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00238394's enrollment target sits among peer trials

44 1322nd of 2000 higher than 669 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00238394, the US trial registry maintained by the National Library of Medicine. NCT00238394 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.