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NCT00237770 · ClinicalTrials.gov registry record · Phase 2

Prevention of Low Blood Pressure in Persons With Tetraplegia

A Phase 2 study, sponsored by US Department of Veterans Affairs.

Completed
Registry status
Phase 2
Development phase
16
Enrollment target

NCT00237770: Completed Phase 2 study, sponsored by US Department of Veterans Affairs.

NCT00237770 is a Phase 2 study that has completed, run by US Department of Veterans Affairs. The registered enrollment target is 16 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (88% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00237770, a Phase 2 study, has completed, sponsored by US Department of Veterans Affairs.

COMPLETED
Registry status
Phase 2
Development phase
16 participants
Enrollment target

Study Summary

The aim of this investigation is to determine the blood pressure response to NOS inhibition, with L-NAME, in persons with tetraplegia compared to non-SCI control subjects and to establish if blood pressure can be increased while upright in those with tetraplegia. If blood pressure is increased with NOS inhibition in persons with tetraplegia, this would improve our treatment of the condition of low blood pressure during seated postures in individuals with tetraplegia.

Primary Outcome

Average systolic blood pressure over 45 minutes at 45 degrees of head-up tilt.

Interventions

  • DRUG N-Nitro L-arginine-methylester (L-NAME)
  • PROCEDURE Head-up Tilt maneuver

Trial Details

FieldValue
Enrollment Target 16 participants
Start Date 2003-06
Est. Completion 2010-06
Phase Phase 2
US Department of Veterans Affairs

632 total trials

What the finished NCT00237770 record still lists

NCT00237770 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (88% lower).

The record links to 0 conditions, and to 2 interventions - of which N-Nitro L-arginine-methylester (L-NAME) is the first listed.

NCT00237770 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00237770 about?

NCT00237770 is a clinical study titled "Prevention of Low Blood Pressure in Persons With Tetraplegia". The aim of this investigation is to determine the blood pressure response to NOS inhibition, with L-NAME, in persons with tetraplegia compared to non-SCI control subjects and to establish if blood pressure can be increased while upright in those with tetraplegia. If blood pressure is increased with ...

What is the current status of trial NCT00237770?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 16 participants. The study started on 2003-06. Estimated completion is 2010-06.

What interventions are being tested in trial NCT00237770?

The interventions under investigation include: N-Nitro L-arginine-methylester (L-NAME) (DRUG), Head-up Tilt maneuver (PROCEDURE).

Who is sponsoring clinical trial NCT00237770?

This trial is sponsored by US Department of Veterans Affairs, which has 632 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00237770's enrollment target sits among peer trials

16 1908th of 2000 higher than 82 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00237770, the US trial registry maintained by the National Library of Medicine. NCT00237770 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.