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NCT00237718 · ClinicalTrials.gov registry record · Phase 2
Provision of Antioxidant Therapy in Hemodialysis (PATH) Study
A Phase 2 study, sponsored by Vanderbilt University.
- Completed
- Registry status
- Phase 2
- Development phase
- 385
- Enrollment target
NCT00237718: Completed Phase 2 study, sponsored by Vanderbilt University.
NCT00237718 is a Phase 2 study that has completed, run by Vanderbilt University. The registered enrollment target is 385 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (189% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00237718, a Phase 2 study, has completed, sponsored by Vanderbilt University.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 385 participants
- Enrollment target
Study Summary
Studies have shown that end stage renal disease (ESRD) patients have higher levels of blood markers which their body makes in response to increased stress and injury. An increase in these markers have been shown to be related to cardiovascular disease and death in ESRD patients. This study will examine whether antioxidant therapy (Vitamin E and alpha lipoic acid) may decrease these markers.
Primary Outcome
F2-iso is a sensitive laboratory assay for serum levels of F2-isoprostane, which is a biomarker of oxidative stress.
Interventions
- DRUG Placebo
- DRUG Alpha, gamma, beta, and delta (mixed) tocopherols
- DRUG Alpha lipoic acid
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 385 participants |
| Start Date | 2006-04 |
| Est. Completion | 2010-09 |
| Phase | Phase 2 |
What the finished NCT00237718 record still lists
NCT00237718 is an interventional study that assigns participants to a tested intervention. The registered 385 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (189% higher).
The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.
NCT00237718 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00237718 about?
NCT00237718 is a clinical study titled "Provision of Antioxidant Therapy in Hemodialysis (PATH) Study". Studies have shown that end stage renal disease (ESRD) patients have higher levels of blood markers which their body makes in response to increased stress and injury. An increase in these markers have been shown to be related to cardiovascular disease and death in ESRD patients. This study will exam...
What is the current status of trial NCT00237718?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 385 participants. The study started on 2006-04. Estimated completion is 2010-09.
What interventions are being tested in trial NCT00237718?
The interventions under investigation include: Placebo (DRUG), Alpha, gamma, beta, and delta (mixed) tocopherols (DRUG), Alpha lipoic acid (DRUG).
Who is sponsoring clinical trial NCT00237718?
This trial is sponsored by Vanderbilt University, which has 430 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00237718's enrollment target sits among peer trials
385 109th of 2000 higher than 1,890 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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