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NCT00233987 · ClinicalTrials.gov registry record · Phase 2

S0410 Tandem Stem Cell Transplantation in Treating Patients With Progressive or Recurrent Hodgkin's Lymphoma

A Phase 2 study, sponsored by SWOG Cancer Research Network.

Completed
Registry status
Phase 2
Development phase
98
Enrollment target

NCT00233987: Completed Phase 2 study, sponsored by SWOG Cancer Research Network.

NCT00233987 is a Phase 2 study that has completed, run by SWOG Cancer Research Network. The registered enrollment target is 98 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (26% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00233987, a Phase 2 study, has completed, sponsored by SWOG Cancer Research Network.

COMPLETED
Registry status
Phase 2
Development phase
98 participants
Enrollment target

Study Summary

RATIONALE: Radiation therapy uses high-energy x-rays to kill cancer cells. Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving chemotherapy with a peripheral stem cell transplant may allow more chemotherapy to be given so that more cancer cells are killed. Tandem (two) autologous stem cell transplants may be an effective treatment for Hodgkin's lymphoma. PURPOSE: This phase II trial is studying how well tandem stem cell transplantation works in treating patients with progressive or recurrent Hodgkin's lymphoma.

Primary Outcome

Measured from date of randomization to date of first observation of progressive disease, or death due to any cause

Interventions

  • DRUG cyclophosphamide
  • DRUG etoposide
  • DRUG melphalan
  • DRUG carmustine
  • PROCEDURE autologous-autologous tandem hematopoietic stem cell transplantation

Trial Details

FieldValue
Enrollment Target 98 participants
Start Date 2005-10
Est. Completion 2017-12
Phase Phase 2
SWOG Cancer Research Network

270 total trials

What the finished NCT00233987 record still lists

NCT00233987 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 98 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (26% lower).

The record links to 0 conditions, and to 5 interventions - of which cyclophosphamide is the first listed.

NCT00233987 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00233987 about?

NCT00233987 is a clinical study titled "S0410 Tandem Stem Cell Transplantation in Treating Patients With Progressive or Recurrent Hodgkin's Lymphoma". RATIONALE: Radiation therapy uses high-energy x-rays to kill cancer cells. Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving chemotherapy with a peripheral stem cell transplant may allow more ch...

What is the current status of trial NCT00233987?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 98 participants. The study started on 2005-10. Estimated completion is 2017-12.

What interventions are being tested in trial NCT00233987?

The interventions under investigation include: cyclophosphamide (DRUG), etoposide (DRUG), melphalan (DRUG), carmustine (DRUG), autologous-autologous tandem hematopoietic stem cell transplantation (PROCEDURE).

Who is sponsoring clinical trial NCT00233987?

This trial is sponsored by SWOG Cancer Research Network, which has 270 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00233987's enrollment target sits among peer trials

98 743rd of 2000 higher than 1,255 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00233987, the US trial registry maintained by the National Library of Medicine. NCT00233987 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.