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NCT00230165 · ClinicalTrials.gov registry record
The Genetics and Functional Basis of Inherited Platelet, White Blood Cell, Red Blood Cell, and Blood Clotting Disorders.
A clinical trial of Glanzmann Thrombasthenia, sponsored by Rockefeller University.
- Recruiting
- Registry status
- 60
- Enrollment target
- 1
- Study location
NCT00230165: Recruiting study of Glanzmann Thrombasthenia, sponsored by Rockefeller University.
NCT00230165 is a study of Glanzmann Thrombasthenia that is actively recruiting participants, run by Rockefeller University. The registered enrollment target is 60 participants. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00230165, a study of Glanzmann Thrombasthenia, is actively recruiting participants, sponsored by Rockefeller University.
- RECRUITING
- Registry status
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
Blood contains red blood cells, white blood cells, and platelets, as well as a fluid portion termed plasma. We primarily study blood platelets, but sometimes we also analyze the blood of patients with red blood cell disorders (such as sickle cell disease), white blood cell disorders, and disorders of the blood clotting factors found in plasma. Blood platelets are small cell fragments that help people stop bleeding after blood vessels are damaged. Some individuals have abnormalities in their blood platelets that result in them not functioning properly. One such disorder is Glanzmann thrombasthenia. Most such patients have a bleeding disorder characterized by nosebleeds, gum bleeding, easy bruising (black and blue marks), heavy menstrual periods in women, and excessive bleeding after surgery or trauma. Our laboratory performs advanced tests of platelet function and platelet biochemistry. If we find evidence that a genetic disorder may be responsible, we analyze the genetic material (DNA and RNA) from the volunteer, and when possible, close family members to identify the precise defect.
Primary Outcome
The initial slope of the increase in light transmission after an agonist is added to a cuvette containing platelet-rich plasma.
Conditions Studied
Study Locations (1)
New York
- Rockefeller University Hospital - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2005-09 |
| Est. Completion | 2030-06 |
What NCT00230165 shows while recruiting
NCT00230165 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 60 participants, a relatively small participant target.
The record links to 1 condition, with Glanzmann Thrombasthenia appearing as the primary indexed condition, and to 0 interventions.
NCT00230165 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT00230165 about?
NCT00230165 is a clinical study titled "The Genetics and Functional Basis of Inherited Platelet, White Blood Cell, Red Blood Cell, and Blood Clotting Disorders.". Blood contains red blood cells, white blood cells, and platelets, as well as a fluid portion termed plasma. We primarily study blood platelets, but sometimes we also analyze the blood of patients with red blood cell disorders (such as sickle cell disease), white blood cell disorders, and disorders o...
What is the current status of trial NCT00230165?
This trial is currently recruiting. The enrollment target is 60 participants. The study started on 2005-09. Estimated completion is 2030-06.
What conditions does trial NCT00230165 study?
This clinical trial studies the following conditions: Glanzmann Thrombasthenia.
Who is sponsoring clinical trial NCT00230165?
This trial is sponsored by Rockefeller University, which has 117 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00230165 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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