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NCT00225732 · ClinicalTrials.gov registry record · Phase 3
Trial of Caldolor for Treatment of Pain in Post-Operative Adult Patients
A Phase 3 study, sponsored by Cumberland Pharmaceuticals.
- Completed
- Registry status
- Phase 3
- Development phase
- 319
- Enrollment target
NCT00225732: Completed Phase 3 study, sponsored by Cumberland Pharmaceuticals.
NCT00225732 is a Phase 3 study that has completed, run by Cumberland Pharmaceuticals. The registered enrollment target is 319 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (59% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00225732, a Phase 3 study, has completed, sponsored by Cumberland Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 319 participants
- Enrollment target
Study Summary
The primary objective of this study of Caldolor (IV ibuprofen) administered to post-operative hospitalized adult patients every 6 hours for 48 hours is to determine the efficacy of Caldolor compared to placebo for the treatment of post-operative pain as measured by reduction in the requirement for the narcotic analgesic, morphine, post surgery
Primary Outcome
Change in the amount of morphine use (in milligrams) by subjects in each treatment group for a 24 hour period post-surgery
Interventions
- DRUG Intravenous ibuprofen
- OTHER Normal saline as placebo comparator
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 319 participants |
| Start Date | 2005-01 |
| Est. Completion | 2008-01 |
| Phase | Phase 3 |
What the finished NCT00225732 record still lists
NCT00225732 is an interventional study that assigns participants to a tested intervention. The registered 319 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (59% lower).
The record links to 0 conditions, and to 2 interventions - of which Intravenous ibuprofen is the first listed.
NCT00225732 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00225732 about?
NCT00225732 is a clinical study titled "Trial of Caldolor for Treatment of Pain in Post-Operative Adult Patients". The primary objective of this study of Caldolor (IV ibuprofen) administered to post-operative hospitalized adult patients every 6 hours for 48 hours is to determine the efficacy of Caldolor compared to placebo for the treatment of post-operative pain as measured by reduction in the requirement for t...
What is the current status of trial NCT00225732?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 319 participants. The study started on 2005-01. Estimated completion is 2008-01.
What interventions are being tested in trial NCT00225732?
The interventions under investigation include: Intravenous ibuprofen (DRUG), Normal saline as placebo comparator (OTHER).
Who is sponsoring clinical trial NCT00225732?
This trial is sponsored by Cumberland Pharmaceuticals, which has 43 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00225732's enrollment target sits among peer trials
319 1087th of 2000 higher than 914 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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