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NCT00222729 · ClinicalTrials.gov registry record · Phase 2
Study of Pemetrexed and Bevacizumab in Patients With Head and Neck Cancer
A Phase 2 study, sponsored by University of Pittsburgh.
- Completed
- Registry status
- Phase 2
- Development phase
- 42
- Enrollment target
NCT00222729: Completed Phase 2 study, sponsored by University of Pittsburgh.
NCT00222729 is a Phase 2 study that has completed, run by University of Pittsburgh. The registered enrollment target is 42 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (68% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00222729, a Phase 2 study, has completed, sponsored by University of Pittsburgh.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 42 participants
- Enrollment target
Study Summary
The purpose of this study is to determine if the combination of two new drugs pemetrexed (Alimta) and bevacizumab (Avastin) can increase the effectiveness of treatment for head and neck cancer. Currently pemetrexed is approved by the Food and Drug Administration (FDA) for another type of cancer, mesothelioma, but it is not approved for head and neck cancer.
Primary Outcome
TTP was calculated from treatment initiation to disease progression or last follow-up.
Interventions
- DRUG Bevacizumab
- DRUG Pemetrexed
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 42 participants |
| Start Date | 2005-11 |
| Est. Completion | 2013-10 |
| Phase | Phase 2 |
What the finished NCT00222729 record still lists
NCT00222729 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 42 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (68% lower).
The record links to 0 conditions, and to 2 interventions - of which Bevacizumab is the first listed.
NCT00222729 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00222729 about?
NCT00222729 is a clinical study titled "Study of Pemetrexed and Bevacizumab in Patients With Head and Neck Cancer". The purpose of this study is to determine if the combination of two new drugs pemetrexed (Alimta) and bevacizumab (Avastin) can increase the effectiveness of treatment for head and neck cancer. Currently pemetrexed is approved by the Food and Drug Administration (FDA) for another type of cancer, mes...
What is the current status of trial NCT00222729?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 42 participants. The study started on 2005-11. Estimated completion is 2013-10.
What interventions are being tested in trial NCT00222729?
The interventions under investigation include: Bevacizumab (DRUG), Pemetrexed (DRUG).
Who is sponsoring clinical trial NCT00222729?
This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00222729's enrollment target sits among peer trials
42 1339th of 2000 higher than 649 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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