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NCT00221351 · ClinicalTrials.gov registry record · NA

C-reactive Protein (CRP)-Guided Management Algorithm for Adults With Acute Cough

A NA study, sponsored by University of California, San Francisco.

Completed
Registry status
NA
Development phase
139
Enrollment target

NCT00221351: Completed NA study, sponsored by University of California, San Francisco.

NCT00221351 is a NA study that has completed, run by University of California, San Francisco. The registered enrollment target is 139 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (90% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00221351, a NA study, has completed, sponsored by University of California, San Francisco.

COMPLETED
Registry status
NA
Development phase
139 participants
Enrollment target

Study Summary

We aim to evaluate the impact of a CRP-guided management algorithm for adults with acute cough illness. More specifically, we will examine both process of care and clinical outcomes: 1. Processes of care (i.e., chest x-rays ordered, antibiotic treatment, length-of-time in the ED). We hypothesize that CRP-guided management will be associated with a decrease in the antibiotic prescription for acute cough illness from 50 percent to 30 percent. 2. Clinical outcomes (i.e., duration of illness, any return visit, return visit with a diagnosis of pneumonia, hospitalization, subsequent antibiotic use, satisfaction with care). We hypothesize that there will be no difference in the proportion of patients feeling back to normal within 2 weeks of their ED visit for acute cough illness (about 60 percent, 95% confidence interval=50 to 70 percent).

Interventions

  • PROCEDURE CRP point of care testing

Trial Details

FieldValue
Enrollment Target 139 participants
Start Date 2005-10
Est. Completion 2006-07
Phase NA

What the finished NCT00221351 record still lists

NCT00221351 is an interventional study that assigns participants to a tested intervention. The registered 139 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (90% lower).

The record links to 0 conditions, and to 1 intervention - of which CRP point of care testing is the first listed.

NCT00221351 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00221351 about?

NCT00221351 is a clinical study titled "C-reactive Protein (CRP)-Guided Management Algorithm for Adults With Acute Cough". We aim to evaluate the impact of a CRP-guided management algorithm for adults with acute cough illness. More specifically, we will examine both process of care and clinical outcomes: 1. Processes of care (i.e., chest x-rays ordered, antibiotic treatment, length-of-time in the ED). We hypothesize th...

What is the current status of trial NCT00221351?

This trial is currently completed. It is a NA study. The enrollment target is 139 participants. The study started on 2005-10. Estimated completion is 2006-07.

What interventions are being tested in trial NCT00221351?

The interventions under investigation include: CRP point of care testing (PROCEDURE).

Who is sponsoring clinical trial NCT00221351?

This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00221351's enrollment target sits among peer trials

139 720th of 2000 higher than 1,281 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00221351, the US trial registry maintained by the National Library of Medicine. NCT00221351 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.