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NCT00220909 · ClinicalTrials.gov registry record · Phase 4

Lansoprazole Preventing Gastroduodenal Stress Ulcerations

A Phase 4 study, sponsored by Temple University.

Terminated
Registry status
Phase 4
Development phase
40
Enrollment target

NCT00220909: Clinical Trial Phase 4 study, sponsored by Temple University.

NCT00220909 is a Phase 4 study that was terminated before completion, run by Temple University. The registered enrollment target is 40 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00220909, a Phase 4 study, was terminated before completion, sponsored by Temple University.

TERMINATED
Registry status
Phase 4
Development phase
40 participants
Enrollment target

Study Summary

The primary objective of this study is to determine whether lansoprazole, administered intravenously, can protect patients undergoing cardiac surgery from the development of and/or progression of previously undetected acid/peptic disorders (erosive esophagitis, gastric ulcer, duodenal ulcer, diffuse gastritis, duodenitis) as measured by the Lanza score and LA classification for esophageal injury. The secondary objectives of this study are: 1. To determine if intravenous lansoprazole protects against the development of clinically important gastrointestinal bleeding in this population (overt bleeding or requiring blood transfusion). 2. To determine if intravenous lansoprazole maintains the intragastric pH above that for placebo throughout the study period.

Interventions

  • DRUG Lansoprazole

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2005-09
Est. Completion 2006-01
Phase Phase 4
Temple University

163 total trials

Why NCT00220909 stopped before completion

NCT00220909 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (92% lower).

The record links to 0 conditions, and to 1 intervention - of which Lansoprazole is the first listed.

NCT00220909 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00220909 about?

NCT00220909 is a clinical study titled "Lansoprazole Preventing Gastroduodenal Stress Ulcerations". The primary objective of this study is to determine whether lansoprazole, administered intravenously, can protect patients undergoing cardiac surgery from the development of and/or progression of previously undetected acid/peptic disorders (erosive esophagitis, gastric ulcer, duodenal ulcer, diffuse...

What is the current status of trial NCT00220909?

This trial is currently terminated. It is a Phase 4 study. The enrollment target is 40 participants. The study started on 2005-09. Estimated completion is 2006-01.

What interventions are being tested in trial NCT00220909?

The interventions under investigation include: Lansoprazole (DRUG).

Who is sponsoring clinical trial NCT00220909?

This trial is sponsored by Temple University, which has 163 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00220909's enrollment target sits among peer trials

40 1397th of 2000 higher than 533 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00220909, the US trial registry maintained by the National Library of Medicine. NCT00220909 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.