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NCT00220467 · ClinicalTrials.gov registry record · Phase 2
Cognitive Effects of Aerobic Exercise for MCI Adults
A Phase 2 study, sponsored by Seattle Institute for Biomedical and Clinical Research.
- Completed
- Registry status
- Phase 2
- Development phase
- 40
- Enrollment target
NCT00220467: Completed Phase 2 study, sponsored by Seattle Institute for Biomedical and Clinical Research.
NCT00220467 is a Phase 2 study that has completed, run by Seattle Institute for Biomedical and Clinical Research. The registered enrollment target is 40 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (70% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00220467, a Phase 2 study, has completed, sponsored by Seattle Institute for Biomedical and Clinical Research.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 40 participants
- Enrollment target
Study Summary
The specific aims for the study will be to determine if aerobic exercise enhances cognition for older adults who are at greater risk for developing Alzheimer's disease, and to evaluate whether change in insulin sensitivity predicts cognitive performance for subjects randomized to the aerobic exercise group. Sedentary older adults diagnosed with mild cognitive impairment will participate in a 6-month supervised protocol of either aerobic exercise or stretching. Cognitive testing and blood collection will occur at baseline, and months 3 and 6. Before and after the 6-month intervention, insulin sensitivity, maximum aerobic capacity, and body fat composition and distribution (via CT scan) will be assessed for all subjects. The results of this study may provide support for a relatively simple and inexpensive treatment strategy that specifically targets many of the health factors that directly influence risk of cognitive decline for older adults.
Interventions
- BEHAVIORAL Aerobic exercise
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2005-01 |
| Est. Completion | 2008-05 |
| Phase | Phase 2 |
What the finished NCT00220467 record still lists
NCT00220467 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (70% lower).
The record links to 0 conditions, and to 1 intervention - of which Aerobic exercise is the first listed.
NCT00220467 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00220467 about?
NCT00220467 is a clinical study titled "Cognitive Effects of Aerobic Exercise for MCI Adults". The specific aims for the study will be to determine if aerobic exercise enhances cognition for older adults who are at greater risk for developing Alzheimer's disease, and to evaluate whether change in insulin sensitivity predicts cognitive performance for subjects randomized to the aerobic exercis...
What is the current status of trial NCT00220467?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 40 participants. The study started on 2005-01. Estimated completion is 2008-05.
What interventions are being tested in trial NCT00220467?
The interventions under investigation include: Aerobic exercise (BEHAVIORAL).
Who is sponsoring clinical trial NCT00220467?
This trial is sponsored by Seattle Institute for Biomedical and Clinical Research, which has 43 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00220467's enrollment target sits among peer trials
40 1362nd of 2000 higher than 542 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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