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NCT00218387 · ClinicalTrials.gov registry record · Phase 2
Modafinil Combined With Cognitive Behavior Therapy to Treat Cocaine Addiction - 1
A Phase 2 study, sponsored by Medical University of South Carolina.
- Completed
- Registry status
- Phase 2
- Development phase
- 123
- Enrollment target
NCT00218387: Completed Phase 2 study, sponsored by Medical University of South Carolina.
NCT00218387 is a Phase 2 study that has completed, run by Medical University of South Carolina. The registered enrollment target is 123 participants, roughly in line with the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00218387, a Phase 2 study, has completed, sponsored by Medical University of South Carolina.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 123 participants
- Enrollment target
Study Summary
Cocaine addiction is a serious health problem with no available medical treatment for preventing relapse. Modafinil, a medication that enhances mood, increases energy, and improves concentration, may be useful in preventing relapse among individuals with cocaine addiction. This study will evaluate the effectiveness of modafinil, in combination with cognitive behavior therapy (CBT), to prevent drug relapse among cocaine addicts.
Primary Outcome
Number of cocaine non-use days was determined by Urine Drug Screen tests which confirmed presence (or no presence) of benzoylecgonine levels.
Interventions
- DRUG Modafinil
- DRUG Matching Placebo
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 123 participants |
| Start Date | 2004-04 |
| Est. Completion | 2010-07 |
| Phase | Phase 2 |
What the finished NCT00218387 record still lists
NCT00218387 is an interventional study that assigns participants to a tested intervention. The registered 123 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target.
The record links to 0 conditions, and to 2 interventions - of which Modafinil is the first listed.
NCT00218387 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00218387 about?
NCT00218387 is a clinical study titled "Modafinil Combined With Cognitive Behavior Therapy to Treat Cocaine Addiction - 1". Cocaine addiction is a serious health problem with no available medical treatment for preventing relapse. Modafinil, a medication that enhances mood, increases energy, and improves concentration, may be useful in preventing relapse among individuals with cocaine addiction. This study will evaluate t...
What is the current status of trial NCT00218387?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 123 participants. The study started on 2004-04. Estimated completion is 2010-07.
What interventions are being tested in trial NCT00218387?
The interventions under investigation include: Modafinil (DRUG), Matching Placebo (DRUG).
Who is sponsoring clinical trial NCT00218387?
This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00218387's enrollment target sits among peer trials
123 564th of 2000 higher than 1,436 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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