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NCT00209027 · ClinicalTrials.gov registry record · NA

The Effects of Aripiprazole on the Processing of Rewards in Schizophrenia

A NA study, sponsored by Emory University.

Terminated
Registry status
NA
Development phase
20
Enrollment target

NCT00209027: Clinical Trial NA study, sponsored by Emory University.

NCT00209027 is a NA study that was terminated before completion, run by Emory University. The registered enrollment target is 20 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00209027, a NA study, was terminated before completion, sponsored by Emory University.

TERMINATED
Registry status
NA
Development phase
20 participants
Enrollment target

Study Summary

The objective of this study is to determine whether subjects with negative symptoms of schizophrenia have abnormal functioning of brain circuits relevant to reward processing, and to determine whether any such abnormalities are normalized by treatment with aripiprazole.

Primary Outcome

fMRI BOLD activation during a reward task will be compared between schizophrenia subjects and controls at Baseline. Schizophrenia subjects will switch their baseline medication to aripiprazole and their BOLD activation during the reward task at Baseline will be compared to the endpoint scan.

Interventions

  • OTHER fMRI
  • DRUG Aripiprazole

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2005-04
Est. Completion 2011-04
Phase NA
Emory University

1,208 total trials

Why NCT00209027 stopped before completion

NCT00209027 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 2 interventions - of which fMRI is the first listed.

NCT00209027 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00209027 about?

NCT00209027 is a clinical study titled "The Effects of Aripiprazole on the Processing of Rewards in Schizophrenia". The objective of this study is to determine whether subjects with negative symptoms of schizophrenia have abnormal functioning of brain circuits relevant to reward processing, and to determine whether any such abnormalities are normalized by treatment with aripiprazole.

What is the current status of trial NCT00209027?

This trial is currently terminated. It is a NA study. The enrollment target is 20 participants. The study started on 2005-04. Estimated completion is 2011-04.

What interventions are being tested in trial NCT00209027?

The interventions under investigation include: fMRI (OTHER), Aripiprazole (DRUG).

Who is sponsoring clinical trial NCT00209027?

This trial is sponsored by Emory University, which has 1,208 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00209027's enrollment target sits among peer trials

20 1768th of 2000 higher than 140 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00209027, the US trial registry maintained by the National Library of Medicine. NCT00209027 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.