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NCT00208143 · ClinicalTrials.gov registry record · Phase 4

Seroquel Therapy for Substance Use Disorders Comorbid With Schizophrenia

A Phase 4 study, sponsored by Creighton University.

Completed
Registry status
Phase 4
Development phase
20
Enrollment target

NCT00208143: Completed Phase 4 study, sponsored by Creighton University.

NCT00208143 is a Phase 4 study that has completed, run by Creighton University. The registered enrollment target is 20 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00208143, a Phase 4 study, has completed, sponsored by Creighton University.

COMPLETED
Registry status
Phase 4
Development phase
20 participants
Enrollment target

Study Summary

It is hypothesized that the atypical antipsychotic, Seroquel, will cause significant reduction in drug and alcohol cravings in patients with schizophrenia and comorbid cocaine and/methamphetamine dependence compared to the atypical antipsychotic, risperidone (Risperdal). Patients treated with Seroquel will have less use of cocaine and/or methamphetamine as measured by the Time Line Follow-back, over a 24-week follow-up period.

Interventions

  • DRUG Risperidone
  • DRUG Quetiapine

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2003-11
Est. Completion 2005-12
Phase Phase 4
Creighton University

98 total trials

What the finished NCT00208143 record still lists

NCT00208143 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (96% lower).

The record links to 0 conditions, and to 2 interventions - of which Risperidone is the first listed.

NCT00208143 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00208143 about?

NCT00208143 is a clinical study titled "Seroquel Therapy for Substance Use Disorders Comorbid With Schizophrenia". It is hypothesized that the atypical antipsychotic, Seroquel, will cause significant reduction in drug and alcohol cravings in patients with schizophrenia and comorbid cocaine and/methamphetamine dependence compared to the atypical antipsychotic, risperidone (Risperdal). Patients treated with Seroq...

What is the current status of trial NCT00208143?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 20 participants. The study started on 2003-11. Estimated completion is 2005-12.

What interventions are being tested in trial NCT00208143?

The interventions under investigation include: Risperidone (DRUG), Quetiapine (DRUG).

Who is sponsoring clinical trial NCT00208143?

This trial is sponsored by Creighton University, which has 98 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00208143's enrollment target sits among peer trials

20 1753rd of 2000 higher than 167 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00208143, the US trial registry maintained by the National Library of Medicine. NCT00208143 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.