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NCT00208091 · ClinicalTrials.gov registry record · Phase 4

Quantifying Musical Performance After Treatment With Myobloc in Musician's Dystonia

A Phase 4 study, sponsored by Columbia University.

Completed
Registry status
Phase 4
Development phase
16
Enrollment target

NCT00208091: Completed Phase 4 study, sponsored by Columbia University.

NCT00208091 is a Phase 4 study that has completed, run by Columbia University. The registered enrollment target is 16 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00208091, a Phase 4 study, has completed, sponsored by Columbia University.

COMPLETED
Registry status
Phase 4
Development phase
16 participants
Enrollment target

Study Summary

This study uses a computerized method of musical instrument digital interface (MIDI) quantification of performance before and after treatment with botulinum toxin type B (Myobloc ®, Solstice Neurosciences). Myobloc is a purified and diluted form of botulinum toxin used medically to relax unwanted muscle spasms and movements. The aim of the study is to determine the feasibility of quantifying change in performance following treatment.

Primary Outcome

Note errors (related to errors in duration in msec) were obtained as measures of difference between the affected and unaffected hands--taking the musical instrument digital interface (MIDI) note output from four musical sequences of 8 to 16 notes played. It was calculated by averaging the sequences for each hand, and deriving the square root of the mean of the square of the differences (root mean square error, in msec) in MIDI.

Interventions

  • DRUG Botulinum toxin, type B

Trial Details

FieldValue
Enrollment Target 16 participants
Start Date 2003-04
Est. Completion 2008-05
Phase Phase 4
Columbia University

958 total trials

What the finished NCT00208091 record still lists

NCT00208091 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (97% lower).

The record links to 0 conditions, and to 1 intervention - of which Botulinum toxin, type B is the first listed.

NCT00208091 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00208091 about?

NCT00208091 is a clinical study titled "Quantifying Musical Performance After Treatment With Myobloc in Musician's Dystonia". This study uses a computerized method of musical instrument digital interface (MIDI) quantification of performance before and after treatment with botulinum toxin type B (Myobloc ®, Solstice Neurosciences). Myobloc is a purified and diluted form of botulinum toxin used medically to relax unwanted mu...

What is the current status of trial NCT00208091?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 16 participants. The study started on 2003-04. Estimated completion is 2008-05.

What interventions are being tested in trial NCT00208091?

The interventions under investigation include: Botulinum toxin, type B (DRUG).

Who is sponsoring clinical trial NCT00208091?

This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00208091's enrollment target sits among peer trials

16 1869th of 2000 higher than 121 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00208091, the US trial registry maintained by the National Library of Medicine. NCT00208091 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.