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NCT00206492 · ClinicalTrials.gov registry record · Phase 2
Trial of ZD1839 (Iressa) and Tamoxifen in Breast Cancer Patients
A Phase 2 study, sponsored by Baylor Breast Care Center.
- Terminated
- Registry status
- Phase 2
- Development phase
- 3
- Enrollment target
NCT00206492: Clinical Trial Phase 2 study, sponsored by Baylor Breast Care Center.
NCT00206492 is a Phase 2 study that was terminated before completion, run by Baylor Breast Care Center. The registered enrollment target is 3 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00206492, a Phase 2 study, was terminated before completion, sponsored by Baylor Breast Care Center.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 3 participants
- Enrollment target
Study Summary
The researchers want to learn whether ZD1839 can improve the activity of tamoxifen, a drug that participants will receive for the treatment of the type of breast cancer being studied. Tamoxifen medicine is part of the standard treatment for the type of breast cancer being studied. It is approved for the treatment of this problem. In order to help the researchers understand how the cancer responds to these medicines, the researchers will take a small tissue sample (biopsy) of the breast cancer before beginning treatment and after two weeks of treatment, at 6 weeks and when surgery is done as part of treatment for the cancer. If participants do not respond to treatment, another biopsy will be done to see why the participants did not respond. These samples will also be collected to look at different characteristics of the cancer. The researchers cannot and do not guarantee that participants will benefit if they take part in this study
Primary Outcome
mechanisms of the cellular response, markers predicting response, by investigating whether ZD1839 with or without tamoxifen treatment is associated with altered biomarkers in cells isolated by core needle biopsy
Interventions
- DRUG Tamoxifen
- DRUG Iressa
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 3 participants |
| Start Date | 2003-07 |
| Est. Completion | 2006-10 |
| Phase | Phase 2 |
Why NCT00206492 stopped before completion
NCT00206492 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 3 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 2 interventions - of which Tamoxifen is the first listed.
NCT00206492 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00206492 about?
NCT00206492 is a clinical study titled "Trial of ZD1839 (Iressa) and Tamoxifen in Breast Cancer Patients". The researchers want to learn whether ZD1839 can improve the activity of tamoxifen, a drug that participants will receive for the treatment of the type of breast cancer being studied. Tamoxifen medicine is part of the standard treatment for the type of breast cancer being studied. It is approved for...
What is the current status of trial NCT00206492?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 3 participants. The study started on 2003-07. Estimated completion is 2006-10.
What interventions are being tested in trial NCT00206492?
The interventions under investigation include: Tamoxifen (DRUG), Iressa (DRUG).
Who is sponsoring clinical trial NCT00206492?
This trial is sponsored by Baylor Breast Care Center, which has 15 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00206492's enrollment target sits among peer trials
3 2001st of 2000 the lowest of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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