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NCT00206206 · ClinicalTrials.gov registry record · NA

Evaluation of an ICU Hyperglycemia Protocol Using Insulin Aspart

A NA study, sponsored by Atlantic Health System.

Terminated
Registry status
NA
Development phase
235
Enrollment target

NCT00206206: Clinical Trial NA study, sponsored by Atlantic Health System.

NCT00206206 is a NA study that was terminated before completion, run by Atlantic Health System. The registered enrollment target is 235 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (83% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00206206, a NA study, was terminated before completion, sponsored by Atlantic Health System.

TERMINATED
Registry status
NA
Development phase
235 participants
Enrollment target

Study Summary

In response to the evidence supporting "tight" glucose control (70 - 110) in the critical care setting, the MMH ICU developed a protocol utilizing regular intravenous insulin. This protocol was initiated in 2002. Monitoring of the data collected revealed effective glycemic control when this protocol was used. However, limited utilization has led to overall ineffective glycemic control in this ICU. The poor utilization is largely due to a general reluctance of physicians to start their patients on an intravenous insulin infusion. As contributing to this poor compliance is the "open" nature of the ICU. The MMH ICU is an "open" ICU, meaning that many physicians across multiple subspecialties admit to this unit. Approaches to controlling hyperglycemia vary greatly, depending largely upon the treating physician. In an attempt to improve overall glycemic control in this "open" ICU, the Subcutaneaous Insulin Aspart Hyperglycemia Protocol (SIAP) was developed which incorporates a subcutaneous insulin aspart regimen that triggers the use of a regular insulin infusion protocol when the SIAP is not adequately controlling the patient's blood glucose. This study aims to evaluate 1) the effect the SIAP on overall glycemic control in the ICU, 2) the effectiveness that the SIAP has on controlling blood glucose as compared with past practices using regular insulin, and 3) the effect the SIAP has on patient complications and outcomes in the MMH ICU.

Interventions

  • PROCEDURE Hyperglycemia Protocol Procedure

Trial Details

FieldValue
Enrollment Target 235 participants
Start Date 2005-07
Phase NA
Atlantic Health System

43 total trials

Why NCT00206206 stopped before completion

NCT00206206 is an interventional study that assigns participants to a tested intervention. The registered 235 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (83% lower).

The record links to 0 conditions, and to 1 intervention - of which Hyperglycemia Protocol Procedure is the first listed.

NCT00206206 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00206206 about?

NCT00206206 is a clinical study titled "Evaluation of an ICU Hyperglycemia Protocol Using Insulin Aspart". In response to the evidence supporting "tight" glucose control (70 - 110) in the critical care setting, the MMH ICU developed a protocol utilizing regular intravenous insulin. This protocol was initiated in 2002. Monitoring of the data collected revealed effective glycemic control when this protocol...

What is the current status of trial NCT00206206?

This trial is currently terminated. It is a NA study. The enrollment target is 235 participants. The study started on 2005-07.

What interventions are being tested in trial NCT00206206?

The interventions under investigation include: Hyperglycemia Protocol Procedure (PROCEDURE).

Who is sponsoring clinical trial NCT00206206?

This trial is sponsored by Atlantic Health System, which has 43 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00206206's enrollment target sits among peer trials

235 461st of 2000 higher than 1,539 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00206206, the US trial registry maintained by the National Library of Medicine. NCT00206206 (mid enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.