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NCT00204945 · ClinicalTrials.gov registry record · NA

Catheterization Laboratory Study: Acute Responses in Diastolic Heart Failure

A NA study, sponsored by University of Wisconsin, Madison.

Completed
Registry status
NA
Development phase
15
Enrollment target

NCT00204945: Completed NA study, sponsored by University of Wisconsin, Madison.

NCT00204945 is a NA study that has completed, run by University of Wisconsin, Madison. The registered enrollment target is 15 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00204945, a NA study, has completed, sponsored by University of Wisconsin, Madison.

COMPLETED
Registry status
NA
Development phase
15 participants
Enrollment target

Study Summary

1. Research question: What is the response of the heart's pumping function to changes in heart chamber pressures? 2. Experimental design: Patients undergoing routine cardiac catheterization will be studied. A thermodilution pulmonary artery catheter will be inserted through a venous sheath and threaded into the pulmonary artery. After several minutes of quiet rest, baseline hemodynamics will be obtained, including a determination of cardiac output using thermodilution techniques and 30 seconds of pressure recordings from the left ventricle and proximal aorta. In addition, a brief echocardiogram will be performed, to determine ejection fraction and indices of diastolic filling. Finally, arterial tonometry will be obtained in quick succession from the brachial, radial, femoral, and carotid arteries. Following the collection of baseline data, a bolus and infusion of nesiritide will be started. After 10 minutes of nesiritide infusion, with the drug still infusing, a full set of invasive hemodynamics will again be obtained, as well as brief echocardiographic and arterial tonometry examinations.

Interventions

  • DRUG nesiritide

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2005-02
Est. Completion 2007-06-20
Phase NA
University of Wisconsin, Madison

1,039 total trials

What the finished NCT00204945 record still lists

NCT00204945 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 1 intervention - of which nesiritide is the first listed.

NCT00204945 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00204945 about?

NCT00204945 is a clinical study titled "Catheterization Laboratory Study: Acute Responses in Diastolic Heart Failure". 1. Research question: What is the response of the heart's pumping function to changes in heart chamber pressures? 2. Experimental design: Patients undergoing routine cardiac catheterization will be studied. A thermodilution pulmonary artery catheter will be inserted through a venous sheath and threa...

What is the current status of trial NCT00204945?

This trial is currently completed. It is a NA study. The enrollment target is 15 participants. The study started on 2005-02. Estimated completion is 2007-06-20.

What interventions are being tested in trial NCT00204945?

The interventions under investigation include: nesiritide (DRUG).

Who is sponsoring clinical trial NCT00204945?

This trial is sponsored by University of Wisconsin, Madison, which has 1,039 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00204945's enrollment target sits among peer trials

15 1881st of 2000 higher than 92 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00204945, the US trial registry maintained by the National Library of Medicine. NCT00204945 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.