Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00203528 · ClinicalTrials.gov registry record · Phase 4

Divalproex ER vs. Risperidone for Bipolar Disorder With Comorbid Substance Use Disorder

A Phase 4 study, sponsored by Tuscaloosa Research & Education Advancement Corporation.

Completed
Registry status
Phase 4
Development phase
30
Enrollment target

NCT00203528: Completed Phase 4 study, sponsored by Tuscaloosa Research & Education Advancement Corporation.

NCT00203528 is a Phase 4 study that has completed, run by Tuscaloosa Research & Education Advancement Corporation. The registered enrollment target is 30 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00203528, a Phase 4 study, has completed, sponsored by Tuscaloosa Research & Education Advancement Corporation.

COMPLETED
Registry status
Phase 4
Development phase
30 participants
Enrollment target

Study Summary

The primary objective is to evaluate the safety and efficacy of divalproex extended release (ER) compared to risperidone in the treatment of bipolar disorder with comorbid substance use disorder

Interventions

  • DRUG risperidone
  • DRUG divalproex sodium ER

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2004-01
Est. Completion 2007-02
Phase Phase 4

What the finished NCT00203528 record still lists

NCT00203528 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (94% lower).

The record links to 0 conditions, and to 2 interventions - of which risperidone is the first listed.

NCT00203528 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00203528 about?

NCT00203528 is a clinical study titled "Divalproex ER vs. Risperidone for Bipolar Disorder With Comorbid Substance Use Disorder". The primary objective is to evaluate the safety and efficacy of divalproex extended release (ER) compared to risperidone in the treatment of bipolar disorder with comorbid substance use disorder

What is the current status of trial NCT00203528?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 30 participants. The study started on 2004-01. Estimated completion is 2007-02.

What interventions are being tested in trial NCT00203528?

The interventions under investigation include: risperidone (DRUG), divalproex sodium ER (DRUG).

Who is sponsoring clinical trial NCT00203528?

This trial is sponsored by Tuscaloosa Research & Education Advancement Corporation, which has 11 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00203528's enrollment target sits among peer trials

30 1552nd of 2000 higher than 367 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT00977977 · 30 participants · Phase 2

    Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy

  • NCT01459107 · 30 participants · Phase 2

    Human Upper Extremity Allotransplantation

  • NCT01666080 · 30 participants · NA

    Second or Greater Allogeneic Hematopoietic Stem Cell Transplant Using Reduced Intensity Conditioning (RIC)

  • NCT01720836 · 30 participants · Phase 1

    Study of the Immune Response of MUC1 (Mucin1) Peptide Vaccine for Non-small Cell Lung Cancer

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00203528, the US trial registry maintained by the National Library of Medicine. NCT00203528 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.