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NCT00200967 · ClinicalTrials.gov registry record · Phase 3
Asthma Clinical Research Network (ACRN) Trial - Long-Acting Beta Agonist Response by Genotype (LARGE)
A Phase 3 study, sponsored by Milton S. Hershey Medical Center.
- Completed
- Registry status
- Phase 3
- Development phase
- 87
- Enrollment target
NCT00200967: Completed Phase 3 study, sponsored by Milton S. Hershey Medical Center.
NCT00200967 is a Phase 3 study that has completed, run by Milton S. Hershey Medical Center. The registered enrollment target is 87 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (89% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00200967, a Phase 3 study, has completed, sponsored by Milton S. Hershey Medical Center.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 87 participants
- Enrollment target
Study Summary
The purpose of this trial is to determine whether regularly scheduled use of an inhaled long-acting beta agonist (salmeterol) in the setting of concomitant use of inhaled corticosteroids (beclomethasone hydroflouroalkane (HFA) inhaler) will have a detrimental effect on asthma control in people who bear the B16-Arg/Arg genotype of the beta-2 adrenergic receptor gene, as compared to people with asthma of similar severity who bear the B16-Gly/Gly genotype.
Primary Outcome
Change between placebo salmeterol and active salmeterol for AM PEF rate
Interventions
- DRUG salmeterol
- DRUG beclomethasone HFA
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 87 participants |
| Start Date | 2004-12 |
| Est. Completion | 2008-02 |
| Phase | Phase 3 |
What the finished NCT00200967 record still lists
NCT00200967 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 87 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (89% lower).
The record links to 0 conditions, and to 2 interventions - of which salmeterol is the first listed.
NCT00200967 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00200967 about?
NCT00200967 is a clinical study titled "Asthma Clinical Research Network (ACRN) Trial - Long-Acting Beta Agonist Response by Genotype (LARGE)". The purpose of this trial is to determine whether regularly scheduled use of an inhaled long-acting beta agonist (salmeterol) in the setting of concomitant use of inhaled corticosteroids (beclomethasone hydroflouroalkane (HFA) inhaler) will have a detrimental effect on asthma control in people who b...
What is the current status of trial NCT00200967?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 87 participants. The study started on 2004-12. Estimated completion is 2008-02.
What interventions are being tested in trial NCT00200967?
The interventions under investigation include: salmeterol (DRUG), beclomethasone HFA (DRUG).
Who is sponsoring clinical trial NCT00200967?
This trial is sponsored by Milton S. Hershey Medical Center, which has 396 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00200967's enrollment target sits among peer trials
87 1742nd of 2000 higher than 256 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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